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The experiments were performed according to our previous report.30 MEF cells were seeded in 24-well plates with Lab-Tek Chamber Slides with a Cover (Nalge Nunc International, Naperville, IL, USA) in 500 μl medium and incubated overnight. Cells were then treated with UCN-01 (6 μM) for...
(f) HexaKO cells were treated with ABT-737 in the presence of Z-VAD for 6 h and then stained with MitoTracker and photographed under a fluorescence microscope Discussion At some time point following apoptotic stimulation, Bax and Bak, the two requisite effectors of MOMP, suddenly turn from ...
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Under normal circumstances, the cellular concen- tration of eIF2a is maintained at low levels. In this study, we demonstrated that under inflammatory stimulation via TNF-a, b-arr2 directly interacted with eIF2a, thus providing a solid basis for the functional consequence of the b-arr2 and ...
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