Results: 106 histology specimens were analyzed from 100 patients, with 36 biopsies (34%) from sarcoidosis tissues and 70 (66%) from other granulomatous disorders. The Cohen Kappa correlations between the two pathologists for SAA staining positivity were excellent (0.85, 0.73- 0.98). The overall ...
Sarcoidosis is known as the “great mimicker” in radiology. Although the presentation of sarcoidosis with multiple pulmonary nodules is rare, it can also mimic metastatic lung lesions. The presence of accompanying mediastinal lymphadenopathy, especially in bilateral hilar and right paratracheal stations...
Sarcoidosis Vasc. Diffuse Lung Dis. 16, 209–214. PubMed CAS Google Scholar O’Donnell, K., Keogh, B., Cantin, A., and Crystal, R. G. (1987) Pharmacologic suppression of the neutrophil component of the alveolitis in idiopathic pulmonary fibrosis. Am. Rev. Respir. Dis. 136, 288–...
Example annotations were taken from the following samples: granuloma—VUILD96MA (sarcoidosis); tertiary lymphoid structure (TLS)—VUILD110LA (CTD-ILD); microscopic honeycombing (partial)—VUILD78MA (IPAF); goblet cell metaplasia—VUILD104MA2 (IPF); hyperplastic AECs—VUILD107MA (IPF); ...
Chapman EM, Gown A, Mazziotta R, Churg A (2012) Pulmonary hyalinizing granuloma with associated elevation in serum and tissue IgG4 occurring in a patient with a history of sarcoidosis. Am J Surg Pathol 36:774–778 Yousem SA, Hochholzer L (1987) Pulmonary hyalinizing granuloma. Am J Clin...
Differential diagnosis should include interstitial lung disease, sarcoidosis, pulmonary edema associated with left-sided heart disease, or misclassification of patients diagnosed as having PAH (group 1).77 Chest high-resolution CT and biopsy of the lungs, depending on suspected underlying disease, may ...
as a novel candidate microbiota component associated with pulmonary sarcoidosis. However, previous research has shown inconsistencies. Earlier studies indicated a higher relative abundance of Atopobium in individuals with non-small cell lung cancer, suggesting an associated increased risk [50]. These ...
Radiation pneumonitis, end-stage sarcoidosis, certain drug toxicities (e.g.: bleomycin, nitrofurantoin, amiodarone, carmustine and methotrexate) and several congenital disorders (e.g.: Hermansky-Pudlak, Gaucher's disease, Niemann-Pick disease and dyskeratosis congenital) are also in the differential....
They included 22 consecutive patients with idiopathic pulmonary fibrosis, sarcoidosis, extrinsic allergic alveolitis, Churg-Strauss syndrome, Wegener granulomatosis, necrotizing sarcoid granu- lomatosis, hypersensitivity drug reaction, desquama- tive interstitial pneumonia-like drug reaction, silicosis, lymph...
Given a scenario of relapsing pulmonary sarcoidosis in a lady with multiple co-morbidities, half of respondents would institute treatment with a variety of immunosuppressants while a half would simply observe. 42% would refer a 57- year old lady with new onset DPLD for a surgical lung biopsy,...