Results: 106 histology specimens were analyzed from 100 patients, with 36 biopsies (34%) from sarcoidosis tissues and 70 (66%) from other granulomatous disorders. The Cohen Kappa correlations between the two pathologists for SAA staining positivity were excellent (0.85, 0.73- 0.98). The overall ...
Sarcoidosis is known as the “great mimicker” in radiology. Although the presentation of sarcoidosis with multiple pulmonary nodules is rare, it can also mimic metastatic lung lesions. The presence of accompanying mediastinal lymphadenopathy, especially in bilateral hilar and right paratracheal stations...
Example annotations were taken from the following samples: granuloma—VUILD96MA (sarcoidosis); tertiary lymphoid structure (TLS)—VUILD110LA (CTD-ILD); microscopic honeycombing (partial)—VUILD78MA (IPAF); goblet cell metaplasia—VUILD104MA2 (IPF); hyperplastic AECs—VUILD107MA (IPF); ...
Sarcoidosis Vasc. Diffuse Lung Dis. 16, 209–214. PubMed CAS Google Scholar O’Donnell, K., Keogh, B., Cantin, A., and Crystal, R. G. (1987) Pharmacologic suppression of the neutrophil component of the alveolitis in idiopathic pulmonary fibrosis. Am. Rev. Respir. Dis. 136, 288–...
as a novel candidate microbiota component associated with pulmonary sarcoidosis. However, previous research has shown inconsistencies. Earlier studies indicated a higher relative abundance of Atopobium in individuals with non-small cell lung cancer, suggesting an associated increased risk [50]. These ...
51,53 This finding has led to the recommendation that isolated bronchoalveolar lavage lymphocytosis should suggest alternative, corticosteroid-responsive diagnoses such as NSIP, sarcoidosis, hypersensitivity pneumonitis, and bronchiolitis obliterans with organizing pneumonia.42 Transbronchial biopsy is limited by ...
Radiation pneumonitis, end-stage sarcoidosis, certain drug toxicities (e.g.: bleomycin, nitrofurantoin, amiodarone, carmustine and methotrexate) and several congenital disorders (e.g.: Hermansky-Pudlak, Gaucher's disease, Niemann-Pick disease and dyskeratosis congenital) are also in the differential....
IPF was the second most common ILD after sarcoidosis consisting of 27.4% of patients (n = 864). Until 1999–2000 the number of IPF cases diagnosed was rising in Italy, but during 2000–2005 this remained constant. There was a slight male predominance in this data (62.6%), which is...
They included 22 consecutive patients with idiopathic pulmonary fibrosis, sarcoidosis, extrinsic allergic alveolitis, Churg-Strauss syndrome, Wegener granulomatosis, necrotizing sarcoid granu- lomatosis, hypersensitivity drug reaction, desquama- tive interstitial pneumonia-like drug reaction, silicosis, lymph...
Given a scenario of relapsing pulmonary sarcoidosis in a lady with multiple co-morbidities, half of respondents would institute treatment with a variety of immunosuppressants while a half would simply observe. 42% would refer a 57- year old lady with new onset DPLD for a surgical lung biopsy,...