(左图)图示肺部朗格汉斯细胞组织细胞增生症患者的典型肺部异常形态特征,包括上肺区优势的小星状结节和/或囊性病变,并相对保留肺底部实质。(右图)35岁女性吸烟者,患有肺部朗格汉斯细胞组织细胞增生症,表现为咳嗽和呼吸困难。正位胸片显示上肺和中肺区小不规则结节为主,其中一些结节呈现中央透亮区(箭头)。 (左图)同...
Pulmonary Langerhans Cell Histiocytosis (PLCH) is a relatively uncommon lung disease that generally, but not invariably, occurs in cigarette smokers. The pathologic hallmark of PLCH is the accumulation of Langerhans and other inflammatory cells in small airways, resulting in the formation of nodular ...
朗格汉斯细胞组织细胞增生症(langerhans cell histiocytosis,LCH)是罕见单核-吞噬系统细胞异常增生性疾病。单核吞噬系统包括吞噬细胞/单核细胞和树突状细胞,朗格汉斯细胞是一种树突状细胞,分布皮肤鳞状上皮、淋巴结、胸腺上皮、支气管黏膜等,通过吞噬、提呈抗原和激活 T 细胞发挥免疫作用。LCH患者朗格汉斯细胞过度活化、异...
Pulmonary Langerhans-cell histiocytosis in adults is a rare condition of unknown etiology characterized by the accumulation of Langerhans cells organized in granulomas involving the distal bronchioles and destroying their walls. It occurs in young subjects who smoke, with frequency peaking between 20 and...
Langerhans cell histiocytosis (LCH) is a rare disease of unknown aetiology. While it may affect any organ of the body, few cases of solitary lung involvement are published in the literature. Here, we report a rare case of pulmonary LCH (PLCH) in an adult. ...
目的 探讨肺郎格罕细胞组织细胞增多症(pulmonary Langerhans cell histiocytosis, PLCH)的临床特征、诊断和治疗。 方法 回顾性分析1999年-2008年4例病理确诊的PLCH。 结果 4例患者均为男性;13～56岁;2例吸烟。临床特征是活动后气短、气胸。胸部CT表现为网格状、囊状或结节状影像。肺活检病理结果:光学显微镜下可见...
Pulmonary langerhans cell histiocytosis in adults: high-resolution CT鈥攑athology comparisons and evolutional changes at CT Kim HJ, Lee KS, Johkoh T, Tomiyama N, Lee HY, Han J, et al. Pulmonary Langerhans cell histiocytosis in adults: high-resolution CT–pathology comparisons and evolutional cha...
The natural history of pulmonary Langerhans cell histiocytosis (PLCH) has been unclear due to the absence of prospective studies. The rate of patients who experience an early progression of their disease is unknown. Additionally, conflicting effects of smoking cessation on the outcome of PLCH have...
Pulmonary Langerhans cell histiocytosis: a comparative study of computed tomography in children and adults. PURPOSE: Langerhans cell histiocytosis is a rare idiopathic disorder, characterized by the infiltration of 1 or more organs by large mononuclear cells. It ... JM Seely,SS Sr,AT Cadavalgoncalves...
Isolated involvement of lungs in the course of Langerhans-cell histiocytosis (LCH) is very rare in childhood. Spontaneous pneumothorax (PTX) may occur during the course which necessitates rapid intervention. We present a 17 months-old girl who was sent with the pre-diagnosis of miliary ...