Puerarin-V prevents the progression of hypoxia-and monocrotaline-induced pulmonary hypertension in rodent modelspulmonary hypertension Di Chen,Hui-fang Zhang,Tian-yi Yuan,Shu-chan Sun,Ran-ran Wang,Shou-bao Wang,Lian-hua Fang,Yang Lyu,Guan-hua Du - 中国药理学报:英文版 被引量: 0发表: 2022年 ...
One strategy is to take advantage of experiments of nature; specifically, to understand the genetic basis for the inter锕妌dividual variation in the pulmonary vascular response to acute and chronic hypoxia. To date, detailed phenotyping of highlanders has focused on haematocrit and oxygen saturation ...
Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease Atelectasis, Middle Lobe Syndrome and Plastic Bronchitis Past History of Adult Bronchitis Animal Models of Cigarette Smoke-Induced Chronic Obstructive Lung Disease Constitutional Factors in Children with Asthma and Recurrent Bronchitis at Schoo...
In this article we provide an update of the current understanding of hypoxia- and non-hypoxia-related pulmonary hypertension, addressing both the pathophysiological understanding of different disease aetiologies as well as the therapeutic options currently available. 展开 ...
hypoxia is widespread during disease (e.g. chronic obstructive pulmonary disease) and ascent to altitude4. In stark contrast, a growing body of evidence suggests that AMPK deficiency may facilitate hypoxic and idiopathic pulmonary hypertension5,6,7, where mechanisms are largely unknown and therapies ...
The overexpression of hypoxia in pericytes contributed to severepulmonary hypertension(PH) and right ventricular hypertrophy, whereas their removal of hypoxia relieved PH, according to Ke Yuan, Ph.D., an associate scientific researcher in Boston Children's Division of Respiratory Diseases Research who ...
Bronchopulmonary dysplasia (BPD) is a major complication in prematurely born infants. Pulmonary hypertension (PH) associated with BPD (BPD-PH) is characterized by alveolar diffusion impairment, abnormal vascular remodeling, and rarefication of pulmonary
Hypoxia and Hyperoxia. Effects on the Newborn Pulmonary Circulation.At birth, the fetal cardiopulmonary system rapidly establishes the lung as the organ of gas exchange by decreasing pulmonary vascular resistance (PVR) and increasing ... S Wedgwood,PT Schumacker,RH Steinhorn - Hypoxia and Hyperoxia...
Pulmonary hypertension (PH) is a serious disease of multiple etiologies mediated by hypoxia, immune stimuli, and elevated pulmonary pressure that leads to vascular thickening and eventual right heart failure. In a chronic hypoxia model of PH, we previously reported the induction of a novel pleiotropi...
Pulmonary hypertension, a complex and multifaceted disease, is characterized by an increase in the vascular pressure within the lung causing shortness of breath, fainting, and, in more severe cases, heart failure. Pulmonary hypertension can originate from either artery or vein.Hypoxiaorthromboembolis...