Here we purify from rat brain actin-cytoskeletal extracts PP1(A) holoenzymes selectively enriched in PP1gamma(1) over PP1beta isoforms and also containing PP1bp134 and PP1bp175. PP1bp134 and PP1bp175 were identified as the synapse-localized F-actin-binding proteins spinophilin (Allen, P...
Clonal heterogeneity can be de- tected using next-generation DNA sequencing (Shah et al., 2009) and has important biological and medical implications (Aparicio and Caldas, 2013; Bedard et al., 2013). First, naive sample extraction strategies will lead to an underestimation ...
Importantly, microsaccade amplitude increased regardless of whether microsaccades were gen- erated before or after cue presentation (Fig 1C, and see Materials and Methods for definitions of pre-cue and rebound periods). Could these increases in microsaccade amplitude be a ...
Thomas Lübberstedt Vol. 49No. 10pp. 1274–1282 The gene action of 2 sugarcane mosaic virus (SCMV) resistance loci in maize, Scmv1 and Scmv2, was evaluated for potyvirus resistance in an isogenic background. All 4 homozygous and 5 heterozygous isogenic genotypes were produced for introgressio...
Fig 2B shows the distribution under the null hypothesis for the same single neuron of panel A (shown in ms for an easy comparison with panel A). We considered a neuron to have a significant slope of the regression line only if its longest interval of consecutive bi...
Bayesian model comparison showed that—in both the foraging and the casino frames—participants' choices depended jointly on the probability of starvation and the ex- pected endpoint value of the outcome, but could not be explained by economic models based on combinations of statistical moments or...
coli K12 has docu- mented 3,409 operons (including singleton genes), 1,878 promoters, 1,940 transcription factor binding sites of 175 transcription factors (TF) in the regulatory region of 703 operons, and 2,697 TF-target gene regulations [53]. Furthermore, more than a...
Thus, second order medial NTS neurons receive multiple inputs through a single chemical class of afferents based on TRPV1 expression – a result that suggests that myelinated and unmyelinated afferents are fully segregated in the medial subnucleus of caudal NTS. Materials and Metho...
ORIGINAL RESEARCH ARTICLE published: 29 October 2014 doi: 10.3389/fpsyg.2014.01201 Action and familiarity effects on self and other expert musicians' Laban effort-shape analyses of expressive bodily behaviors in instrumental music performance: a case study approach Mary C. Broughton1*...
Under sham dual-tDCS, eight out of 18 stroke patients exhib- ited LI degradation during the Training period. The remaining 10 patients improved, as shown by the evolution of their veloc- ity and error: 7 of them presented a fit pattern and three a shift pattern (Tabl...