Define ptotic. ptotic synonyms, ptotic pronunciation, ptotic translation, English dictionary definition of ptotic. n. pl. pto·ses Abnormal lowering or drooping of an organ or a part, especially a drooping of the upper eyelid caused by muscle weakness or
These differences appear to be due to a decline in eWAT and iWAT mass, as there was no difference in the weights of the liver, heart, spleen, or kidney (Figure 2L) in the RSL3-treated mice compared with the vehicle-treated mice. We also found that 4-HNE staining (Figures 2M and ...
Mice were euthanized via carbon dioxide asphyxiation. Bipedal reflexes were checked to ensure death. A single 5 cm incision was made on midline of abdomen, left and right epididymal fat pad were pulled away from the body so testes can be pulled out of scrotum and cut away from epididymis ...
Elevated interferon (IFN) signaling is associated with kidney diseases including COVID-19, HIV, and apolipoprotein-L1 (APOL1) nephropathy, but whether IFNs directly contribute to nephrotoxicity remains unclear. Using human kidney organoids, primary endothelial cells, and patient samples, we demonstrate...
(right) over 10 days.N = 3, 2 way Anova with Bonferroni correction for multiple comparisons; (b) Competition growth assays measuring the ratio of mCherry positive to mCherry negative cells between WT THP1 (mCherry negative) and NT gRNA or MPI gRNA5 (mCherry positive) with and ...
Acute kidney injury ALI: Acute lung injury CCI: Controlled cortical impact Cox-2: Cyclooxygenase-2 DMEM: Dulbecco’s Modified Eagle’s Medium Fe2+ : Ferrous ion GBD: Global burden of disease ICV: Intracerebroventricular injection LDH: Lactate dehydrogenase MDA: Malondialdehyde miRNAs...
kidney18,19, liver19, intestine20, and brain21. In ischemic diseases, the pathological lesion gradually extends even without complete obliteration22,23,24. While repeated ischemic attacks are considered the cause of this extension of the affected area, it is also possible that pathological lesions ...
M. Effect of Terminalia chebula aqueous extract on oxidative stress and antioxidant status in the liver and kidney of young and aged rats. Cell Biochem Funct 27, 358–363 (2009). 20. Han, Q., Song, J., Qiao, C., Wong, L. & Xu, H. Preparative isolation of hydrolysable tannins ...
We also performed LC-MS analyses of peroxidized PE species in non-cancerous cells: human airway epithelial cells, human kidney epithelial cells, human HK2 kidney cells, H109 human fibroblasts, placental trophoblasts, mouse embryonic fibroblasts, mouse hippocampal HT22 neuronal cells, mouse ...
Two weeks before the study, the right kidney was removed through a small flank incision under pentobarbital anesthesia (50 mg/kg i.p.). After a 2-week recovery period, the mice were anesthetized with pentobarbital (50 mg/kg i.p.) and the left kidney was exposed through a small flank ...