For instance, during the process of immunogenic cell death (ICD), the release of danger signals from tumor cells can recruit CD8 + T cells, potentially enhancing the efficacy of ICB as a cytotoxic lymphocyte-mediated mechanism [17]. Necroptosis of tumor-associated fibroblasts (CAFs) induces...
chemotherapy can induce ICD, activate the adaptive immune response, and reduce the suppression of tumor-infiltrating lymphocytes by the TME, thereby enhancing the effectiveness of immunotherapy [169]. The combination of ICIs with radiotherapy, targeted therapy, adoptive cell therapy, and the next genera...
Immune checkpoint inhibitors (ICIs) targeting PD-1, PD-L1, and CTLA-4 have revolutionized cancer treatment. In disulfidptosis-associated subtypes, high expression of PD-L1 and CTLA-4 correlates with poor prognosis but also indicates that disulfidptosis may induce immunogenic cell death (ICD), ...
Levels of immune cell infiltration and TME characteristics between the two ICDRS groups. (A) Correlation between Dis score and immune cell types. In addition, correlation of signature genes and immune cell infiltration in the Dis score model. (B) Correlation between Dis score and TME score. (...
Deidentified patient data from a 10-year time period was obtained from the electronic medical records of 5 large academic medical centers. Patients were selected based on ICD9 and ICD10 codes for involutional ptosis. Control patients were age and gender matched and randomly selected from a ...
【疾病名】肾下垂【英文名】nephroptosis【缩写】【别名】【ICD号】N39.8【概述】正常肾盂的位置在第1、2腰椎之间,左肾稍高于右肾,肾脏可随呼吸、体..