To investigate the effect of serine protease in excretory-secretory antigens(ES) antigens of adult Trichinella spiralis on the host's immune system,full length sequence of serine protease gene Zh68 was amplified by PCR.The PCR products was cloned into pET28a vector,and the positive recombinant ...
The Paid time off (PTO) policy refers to the printed paper about rules and regulations involving the employee’s paid time away from work. Generally, this policy will include vacation days,sick leave, and personal days, although some companies may have separate banks for each. The primary purp...
Cash or Cash Equivalents means (a) cash; (b) marketable direct obligations issued or unconditionally guaranteed by the United States Government or issued by an agency thereof and backed by the full faith and credit of the United States, in each case maturing within one (1) year after the da...
2. The bearings are optimized in the form of labyrinth, so that dust is not easy to enter. The bearings are equipped with automatic lubrication device, which does not need manual lubricating oil filling. 3. Optimize the electrical system, adopt automatic control...
Full size image αESA enhanced the toxicity of GPX4 inhibitors in multiple cell lines (Fig. 4d and Supplementary Fig. 3), suggesting that the reduction of hydroperoxides by GPX4 opposes αESA-induced ferroptosis. Consistent with this model, transient knockdown of GPX4 by siRNA also enhanced cell...
In the present study, we explored the potential role of ferroptosis, a novel nonapoptotic form of cell death, in SMC phenotypic switch and related neointimal formation. We found that ferroptotic stress was triggered in cultured dedifferentiated SMCs and arterial neointimal tissue of wire-injured ...
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(CST), anti-phospho-IRE1α (GeneTex), anti-phospho-MKK4 (CST), anti-JNK (CST), anti-phospho-JNK1/2/3 (CST), anti-c-Jun (CST), anti-phospho-c-Jun (CST), anti-full caspase-3 (Santa Cruz), anti-cleaved caspase-3 (CST), anti-RIPK1 (R&D Systems) and anti-RIPK3 (CST)....
Full size image Ferroptotic waves in the limb zeugopod As ferroptosis has the potential to propagate over large areas, we examined whether the above-described large-scale cell death could be caused by ferroptosis waves. To this end, we used an ex vivo limb culture system (Methods) to monito...