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To further assess whether WETC affects the upstream signaling events of the necroptotic pathway, we exam- ined its effects on the formation of TNFR1 signaling complex. Notably, in the presence of WETC, TNF-induced recruitment of TRADD and hyperubiquitinated RIP1 into TNFR1 were found to be ...
“Exam not available” means the patient did not attend this follow-up, but may have attended a later one. PP: per-protocol population; ITT: intent-to-treat population. Figure 2 shows the disposition of the angiographic data collected from ITT and PP patients. Angiographic assessments were ...