PTM-SEA PTM-Signature Enrichment Analysis (PTM-SEA) is a modified version of ssGSEA to perform site-specific signature analysis by scoring PTMsigDB's bi-directional signature-sets. The input to PTM-SEA is a single site-centric data matrix,m, stored inGCT v1.2orGCT v1.3format and PTM signa...
Previously, we developed SAPH-ire (Structural Analysis of PTM Hotspots) - a method for the prioritization of PTM function potential that has been used effectively to reveal novel PTM regulatory elements in discrete protein families (Dewhurst et al., 2015). Here, we apply SAPH-ire to the set ...
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PTM-SEA PTM-Signature Enrichment Analysis (PMT-SEA) is a modified version of ssGSEA to perform site-specific signature analysis by scoring PTMsigDB's bi-directional signature-sets. The input to PTM-SEA is a single site-centric data matrix,m, stored inGCT v1.2orGCT v1.3format and PTM signa...
Previously, we developed SAPH-ire () - a method for the prioritization of PTM function potential that has been used effectively to reveal novel PTM regulatory elements in discrete protein families (Dewhurst , 2015). Here, we apply SAPH-ire to the set of eukaryotic protein families containing ...