蛋白质翻译后修饰组学技术(PTMomics)
Prior analysis of intact and modified protein forms (proteoforms) of KRAS4B isolated from cell lines and tumor samples by top-down mass spectrometry revealed the presence of novel posttranslational modifications (PTMs) and potential evidence of context-specific KRAS4B modifications. However, low ...
PTMScout, a Web Resource for Analysis of High Throughput Post-translational Proteomics Studies The rate of discovery of post-translational modification (PTM) sites is increasing rapidly and is significantly outpacing our biological understanding of t... KM Naegle,M Gymrek,BA Joughin,... - 《Molecu...
蛋白质翻译后修饰组学技术(PTMomics).pdf,(PTMomics) 1 Outline 1. PTMomics analysis with mass spectrometry 2. Phosphoproteomics 3. Glycoproteomics 4. Other PTM modifications 2 Outline 1. PTMomics analysis with mass spectrometry 2. Phosphoproteomics 3. Glyco
visualization visualisation pca data-analysis ptm fcs umap mass emd cytof cytometry signalling cytobank ptms organoids cell-communication-lab scprep dremi tape-lab Updated Dec 7, 2023 Python SoftwareSystemsLaboratory / PTMTorrent Star 6 Code Issues Pull requests Code to generate the PTMTorrent da...
Indeed, based on our analysis, the vast majority of PTMs do not exhibit high function potential (Fig. 5). This observation may or may not be a reflection of the source data—including the quality of sample preparation before proteomics mass spectrometry, the quality of PTM identification and ...
14. Feist P, Hummon AB. Proteomic challenges: sample preparation techniques for microgram-quantity protein analysis from biological samples. Int J Mol Sci. 2015;16(2):3537-63. 15. Parker CE, Mocanu V, Mocanu M, Dicheva N, Warren MR. Mass Spectrometry for Post-Translational Modifications. In...
Can be used with a wide range of Python libraries for custom analysis.Proceedings 64th Annual ASMS Conference on Mass Spectrometry and Allied Topics, Vol.1: San Antonio(US).June 6-9, 2016Amin A MominHailey E HautMichela CapelloJuan ChenHong WangSamir M. Hanash...
3. Zhao Y, Jensen ON. Modification-specific proteomics: strategies for characterization of post-translational modifications using enrichment techniques. Proteomics. 2009;9(20):4632-41.4. Bonilla L, Means G, Lee K, Patterson S. The evolution of tools for protein phosphorylation site analysis: ...