This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence...
gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, ...
Elevation of AP production resulted from PBAN injection, while RNA interference (RNAi) of the gene expression suppressed AP production in both sexes. A theoretical biosynthetic pathway to produce AP components was determined, and the involved enzymes' expression was validated experimentally. Individual ...
PTK2/FAK Gene PTK2 cDNA / gene is a gene with protein product which located on 8q24.3. The PTK2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, and frog. 204 organisms have orthologs with human gene PTK2. ...
Research has shown that focal adhesion kinase (FAK), produced by the protein tyrosine kinase 2 (PTK2) gene, is crucial in IPF development. FAK activation is a characteristic of lesional fibroblasts; Thus, FAK may be a valuable therapeutic target or prognostic biomarker for IPF. This study ...
该编码蛋白是蛋白酪氨酸激酶fak亚家族的一员,但与其它亚家族的激酶缺乏明显的序列相似性。该基因的激活可能是细胞生长和细胞内信号转导途径中的一个重要的早期步骤,它是对某些神经肽或细胞与细胞外基质相互作用的反应。已经发现了一些编码不同亚型的转录变体。[由RefSeq提供,2017年6月]This gene encodes a ...
Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010] [中文简述(自动翻译):] 这个基因编码被发现集中在细胞外基质成分的存在下生长的细胞之间形成的粘着斑细胞质蛋白...
Ensembl Gene ID ENSG00000169398.20 Ensembl mRNA ID PTK2-228 包装清单: 产品编号 产品名称 包装 QH05189S Human PTK2 qPCR Primer Pair 1nmol each — 说明书 1份 保存条件: -20℃保存。建议复溶后进行适当分装,避免反复冻融。 注意事项: PCR扩增产物的长度可能会因基因转录后存在多种剪接形式而有所差异...
Gene ID: 5747 种属: Homo sapiens 基因序列编号: NM_153831.4 基因描述: PTK2 protein tyrosine kinase 2 [ Homo sapiens (human) ] DNA大小: 4145 bp 基因编码区: atatgacagatacctagcatctagcaaaataatggcagctgcttaccttgaccccaacttgaatcacacaccaaattcgagtactaagactcacctgggtactggtatggaacgttctcctggtgcaatggagcga...
Our initial genome-wide association study (GWAS) demonstrated that two SNPs (ARS-BFGL-NGS-33248, UA-IFASA-9288) within the protein tyrosine kinase 2 (PTK2) gene were significantly associated with milk production traits in Chinese Holstein dairy cattle. To further validate if the statistical evid...