This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence...
gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, ...
Posttranslational modifications have recently assumed the role of major biological regulators, leading to the substantial escalation in complexity during gene expression and regulation. In vivo, nearly every protein's function is ultimately regulated by molecular switches that modulate their structure, activi...
Research has shown that focal adhesion kinase (FAK), produced by the protein tyrosine kinase 2 (PTK2) gene, is crucial in IPF development. FAK activation is a characteristic of lesional fibroblasts; Thus, FAK may be a valuable therapeutic target or prognostic biomarker for IPF. This study ...
gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, ...
该编码蛋白是蛋白酪氨酸激酶fak亚家族的一员,但与其它亚家族的激酶缺乏明显的序列相似性。该基因的激活可能是细胞生长和细胞内信号转导途径中的一个重要的早期步骤,它是对某些神经肽或细胞与细胞外基质相互作用的反应。已经发现了一些编码不同亚型的转录变体。[由RefSeq提供,2017年6月]This gene encodes a ...
货号产品名称Method规格价格货期 CDS-P05256-11rAd-PTK2重组过表达腺病毒10^10 vg/支￥25003-5周 CDS-P05256-12rAd-sh-PTK2重组干扰腺病毒10^10 vg/支￥25003-5周 CDS-P05256-13rAd-mir30-sh-PTK2重组mir30干扰腺病毒10^10 vg/支￥25003-5周 ...
Gene ID: 5747 种属: Homo sapiens 基因序列编号: NM_153831.4 基因描述: PTK2 protein tyrosine kinase 2 [ Homo sapiens (human) ] DNA大小: 4145 bp 基因编码区: atatgacagatacctagcatctagcaaaataatggcagctgcttaccttgaccccaacttgaatcacacaccaaattcgagtactaagactcacctgggtactggtatggaacgttctcctggtgcaatggagcga...
Entrez Gene ID:(Human) 2185 Cookie设置 我们及我们的关联方等通过运用Cookie等技术来为您提供您感兴趣的网站定制内容、识别访问者、保障安全登录和收集数据。点击“全部接受”以接受所有 cookie 并直接跳转至网站,或点击“管理设置”以查看 cookie 类型的详细说明,并选择是否在网站上接受某些 cookie。
Our initial genome-wide association study (GWAS) demonstrated that two SNPs (ARS-BFGL-NGS-33248, UA-IFASA-9288) within the protein tyrosine kinase 2 (PTK2) gene were significantly associated with milk production traits in Chinese Holstein dairy cattle. To further validate if the statistical evid...