PTGS2基因单核苷酸多态性与肿瘤的关联研究进展前列素内环氧化物合成酶2(prostaglandinendoperoxidesynthase2PTGS2)在人类许多良性癌前病变和恶性肿瘤中均有高表达,能促进肿瘤血管生成,上皮细胞去分化,增强肿瘤细胞侵袭转移潜能、抑制细胞凋亡等生物过程。而全基因组关联研究发现单核苷酸多态性(singlenucleotidepolymorphismSNP)...
and Szczeklik,A,Functional effects and gender association of COX-2 gene polymorphism G-765 C in bronchial asthma. Journal of allergy and clinical immunology,2004. 114(2):248-253. [3]Papafili,Anastasia,Hill,Michael R,Brull,David J,et al. Common promoter variant in cyclooxygenase-2 represses ...
NONSTEROIDAL ANTIINFLAMMATORY DRUGS LOW-DOSE ASPIRIN COLORECTAL-CANCER PHYSICAL-ACTIVITY INFLAMMATORY RESPONSE CYCLOOXYGENASE-2 GENE SELECTIVE-INHIBITION PROMOTER VARIANT BRONCHIAL-ASTHMA FAMILY REGISTRY DOI: 10.1007/s10552-013-0282-1 被引量: 49 年份...
Exacerbating factors induce different gene expression profiles in peripheral blood mononuclear cells from asthmatics, patients with chronic obstructive pul... Results: rDer p 1 significantly up-regulated the expression of PLA2G4A, PLA2G6, PLA2G15, CYSLTR1, LB4R2, PTGS1, PTGS2, FOXP1, GATA3...
and Szczeklik,A,Functional effects and gender association of COX-2 gene polymorphism G-765 C in bronchial asthma. Journal of allergy and clinical immunology,2004. 114(2):248-253. [3]Papafili,Anastasia,Hill,Michael R,Brull,David J,et al. Common promoter variant in cyclooxygenase-2 represses ...