即pgr、ncoa2、nr3c2、ptgs1、esr1、ptgs2 孕酮受体(PGR)主要在生殖系统发挥作用,女性体内的孕酮水平变化直接影响其功能。怀孕期间孕酮浓度上升,该受体参与胚胎着床和维持妊娠,异常表达可能导致流产或子宫内膜异位症。现有药物黄体酮通过激活该受体保胎,但部分患者出现耐药现象,具体机制尚未完全明确。 核受体共激活因子2(
MAKAR K W, POOLE E M, RESLER A J, et al. COX- 1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations [J]. Cancer Causes Control, 2013, 24(12): 2059-2075....
机译:PTGS1,PTGS2,ALOX5,ALOX12,ALOX15和FLAP SNP:与脂肪酸在结肠癌和直肠癌中的相互作用 2. COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations [J] . MakarK.W., PooleE.M., ReslerA.J., Cancer ca...
PTGS1, PTGS2, ALOX5, ALOX12, ALOX15, and FLAP SNPs: Interaction with fatty acids in colon cancer and rectal cancer. Genes Nutr. 2013, 8, 115-126. [CrossRef] [PubMed]Habermann N, Ulrich CM, Lundgreen A, Makar KW, Poole EM, et al. 2013. PTGS, PTGS2, ALOX5, ALOX12, ALOX15,...
Therefore, we performed a meta-analysis to evaluate the association between the PTGS1 and PTGS2 polymorphisms and the effect of NSAID use on the risk of developing cancer. Methods: We conducted a comprehensive search in PubMed through March 2012. The odds ratios...
Genetic variants in TNFα, TGFB1, PTGS1 and PTGS2 genes are associated with diisocyanate-induced asthmaCytokinediisocyanatesinflammationoccupational asthmasingle nucleotide polymorphism (SNPare the most common cause of , but risk factors are not well defined. A case-control study was conducted to ...
Overexpression of COX (PTGS1 and PTGS2) and COX-related genes in OSCC versus adjacent normal oral tissues.Xinjian PengWenping LiWilliam D. JohnsonKaren E. O. TorresDavid L. McCormick
Association of Single Nucleotide Polymorphisms in PTGS1 and PTGS2 with Aspirin-Induced Urticaria/Angioedemadoi:10.1016/j.jaci.2018.12.203Jurado-Escobar, RaquelDoña, InmaculadaPerkins, James R.Bogas, GadorPérez-sanchez, NataliaBartra, JoanIsidoro-García, María...
Chulada PC, Thompson MB, Mahler JF, Doyle CM, Gaul BW, Lee C, Tiano HF, Morham SG, Smithies O, Langenbach R (2000) Genetic disruption of Ptgs-1, as well as of Ptgs-2, reduces intestinal tumorigenesis in Min mice. Cancer Res 60:4705–4708...