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(G0). The nuclear expression of Ki67 can be evaluated to assess tumor proliferation by IHC (Figure 4). Ki67 is a popular proliferation marker and is routinely used in pathology labs due to its diagnostic and prognostic power in cancer. Recent studies have reported an association between high ...
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Since the development of these techniques, various labs have successfully immunostained cleared tissue, suggesting that this is indeed a viable method (e.g., Chung et al., 2013; Zhang et al., 2014). Still, not much has been said about the potential for multiple rounds of label beyond the...