作为Echelon Biosciences全国总代理,艾美捷科技强烈推荐Echelon热销产品纯化的抗PtdIns(3,4,5)P3单克隆抗体。产品仅用于科研,不可用于临床诊断。 产品名称货号详情 纯化的抗PtdIns(3,4,5)P3单克隆抗体EEB-Z-P345查看 纯化的抗PtdIns(3,4,5)P3单克隆抗体。
Therefore, endosome maturation couples nutrient signaling to lysosome repopulation during basal autophagy by delivering PI3K alpha-derived PtdIns3P to endolysosomes for PtdIns(3,5)P-2-dependent lysosome reformation.doi:10.1080/15548627.2022.2124499Rodgers, Samuel J....
全球有 1家供应商PIK3C3 (VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC:2.7.1.137), PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34)国内生产厂家 ...
英文名称:PIK3C3 (VPS34, Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC:2.7.1.137), PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3, Phosphatidylinositol 3-kinase p100 subunit, Phosphoinositide-3-kinase class 3, hVps34) ...
Phosphoinositide 3-kinase (PI3K), PTEN and localized phosphatidylinositol (3,4,5)-trisphosphate [PtdIns(3,4,5)P3] play key roles in chemotaxis, regulating ... V Kolsch,PG Charest,RA Firtel - 《Journal of Cell Science》 被引量: 516发表: 2008年 ...
Galvez T, Teruel MN, Do Heo W, Jones JT, Kim ML, Liou J, Myers JW, Meyer T. siRNA screen of the human signaling proteome identifies the PtdIns (3, 4, 5) P. Genome Biol. 2007; 8 :R142. doi: 10.1186/gb-2007-8-7-r142. [ Cross Ref ]Galvez, T, Teruel, MN, Heo, WD, ...
Thus, we present the first comprehensive analysis of the PtdIns(3,4,5)P3 signalosome of human platelets and identify DAPP1 as a novel negative regulator of platelet function. This work provides important new insights into how class I PI3Ks shape platelet function.doi:10.1182/bloodadvances....
2 that PtdIns3P substrate deprivation and reduced PtdIns(3,5)P2 synthesis by PIKfyve are causing the endomembrane defect. Combined data support the notion that under induced conditions, class I PI3Ks could deliver to some extent the PtdIns3P precursor for PIKfyve function. 4. Discussion The ...
PI3KLysosomeThe phosphinositide PtdIns(3)P plays an important role in autophagy; however, the detailed mechanism of its activity remains unclear. Here, we used a Systematic Evolution of Ligands by EXponential enrichment (SELEX) screening approach to identify an RNA aptamer of 40 nucleotides that ...
PtdIns(3,4,5)P3-stimulated ROS formation was also inhibited by N17-Rac1, although less efficiently than for PI3K-stimulated ROS formation (mean of 35%, data not shown). The above data suggest that Rac can act downstream of p101/p110γ-PI3K, Gβγ, and PtdIns(3,4,5)P3 in ...