Clinical samples were analysed either on the Roche Elecsys ® Immunoassay using a Cobas E801 analyser or using the Fujirebio Innotest ® as part of routine clinical practice. For the current study, as we were evaluating the performance of p-tau217 to detect Aβ and tau pathology, Aβ ...
The final cloned and purified monoclonal antibody (ADx253) was characterized on synthetic peptides, spanning amino acids Thr217 to Ser241 of full-length tau, for its affinity, its phospho-specificity, using both phosphorylated and nonphosphorylated peptides, and its preferred selectivity in which ...
45. Plasma p-tau217 was quantified using the Mesoscale Discovery platform with an assay developed by Lilly Research Laboratories. Biotinylated-IBA493 was used as a capture antibody and SULFO-TAG-4G10-E2 (anti-tau) as the detector antibody, with sample and antibody dilution at 1:2, as previou...
In the article in this issue, "Quality monitoring approach for optimizing antinuclear antibody screening cutoffs and testing work flows," Tacker and Perrotta address an issue faced by many laboratories鈥攈ow to offer antinuclear antibody... SW Cotten,MR Snyder - 《Journal of Applied Laboratory Medi...
https://ror.org/003dqcp70grid.420287.b0000 0004 0626 367XFujirebio Europe NV Ghent BelgiumWiesje M. van der Flierhttps://ror.org/01x2d9f70grid.484519.5Alzheimer Center, Department of NeurologyAmsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Neuroscience Amsterdam The Netherlands...