④额颞叶痴呆行为变异型(bvFTD,15%):淡漠、执行功能受损(如applause征)、晚期垂直性核上性凝视麻痹,PPV不高(low); ⑤进行性非流利性失语(PNFA,5%),PPV不高(low); ⑥皮质基底综合征(10%):至少一项大脑皮质症状(失用、皮层感觉缺失、异己手),以及至少一项锥体外系表现(少动、肌强直、肌张力障碍、肌阵挛)。
④额颞叶痴呆行为变异型(bvFTD,15%):淡漠、执行功能受损(如applause征)、晚期垂直性核上性凝视麻痹,PPV不高(low); ⑤进行性非流利性失语(PNFA,5%),PPV不高(low); ⑥皮质基底综合征(10%):至少一项大脑皮质症状(失用、皮层感觉缺失、异己手),...
④额颞叶痴呆行为变异型(bvFTD,15%):淡漠、执行功能受损(如applause征)、晚期垂直性核上性凝视麻痹,PPV不高(low); ⑤进行性非流利性失语(PNFA,5%),PPV不高(low); ⑥皮质基底综合征(10%):至少一项大脑皮质症状(失用、皮层感觉缺失、异己手),以及至少一项锥体外系表现(少动、肌强直、肌张力障碍、肌阵挛)。
Methods Patients with PSP, PNFA and LPA were recruited. Patients were diagnosed clinically but pathological confirmation was available in a proportion of patients. Midbrain and pons areas were measured using Osirix Lite, a free DICOM viewer, and M/P was calculated. Results Seventy-two participants...
RESULTS: Of 127 cases analyzed, 57 had a pathologic diagnosis of FTLD, 49 PSP, and 21 CBD. Of these, 38 were clinically reclassified as frontal variant frontotemporal dementia (FTD), 13 as progressive non-fluent aphasia (PNFA), 21 as CBD-like, 33 as PSP-like, and 13 with ...