Comparative analysis of disease outcomes: Early vs. late transition from psoriasis to psoriatic arthritis Objectives Psoriasis typically precedes psoriatic arthritis (PsA). We explored whether the interval between the two diagnoses is associated with PsA phenotype and outcomes. Methods We constructed an ...
Individuals with cutaneous psoriasis (PsC) have an elevated risk of developing psoriatic arthritis (PsA) during their lifetime. Despite this known association, the cellular and molecular mechanisms underlying this progression remain unclear. Methods. We performed high-dimensional, in-dept...
Psoriatic arthritis was less frequent in African-Americans compared to Caucasians (30 vs. 64.5%, respectively, p <0.001); however, African-Americans had more severe skin involvement [Psoriasis Area and Severity Index 8.4 (10.0) vs. Caucasians 5.5 (6.4), p =0.06], with greater psychological ...
Background Apremilast is the first oral selective inhibitor of phosphodiesterase 4 (PDE4) indicated for adults with active psoriatic arthritis (PsA) and moderate to severe plaque psoriasis (Pso). Pso and PsA are chronic disorders with significant morbidity, and patients experience diminished health ...
PSORIATIC arthritisPSORIASISDear Editor, Biosimilar therapies are an emerging option in the treatment of psoriasis and other immune-mediated diseases due to the lower impact on public health costs. SB5, commercially known as imraldi (Samsung Bioepsis), is approved in Europe for the treatment of ...
If granted, guselkumab will be approved to treat children ages 6 and younger with severe plaque psoriasis and children ages 5 and younger with juvenile psoriatic arthritis. Advancements in Psoriasis Therapies with Jason Hawkes, MD, MS Maddi Hebebrand, MC, Associate Editor;Jason E. Hawkes, MD, ...
T. Genetic epidemiology of psoriasis and psoriatic arthritis. Ann. Rheum. Dis. 64 (Suppl. 2), ii37–ii39; discussion ii40–ii41 (2005). This review describes our current understanding of the genetic contributions to psoriasis and PsA and the techniques used in determining these contributions....
Psoriatic arthritisis a condition where you have both psoriasis andarthritis(jointinflammation). In more than 80% of cases, people had psoriasis for an average of 12 years before getting psoriatic arthritis. About 90% of people with psoriatic arthritis also have nail changes. ...
The aim of this study was to characterize interleukin 17 (IL-17) and interleukin 22 (IL-22) producing cells in peripheral blood (PB), skin, synovial fluid (SF) and synovial tissue (ST) in patients with psoriasis (Ps) and psoriatic arthritis (PsA). Flow c
This systematic review and meta-analysis evaluates the association between cancer and psoriasis or psoriatic arthritis.