In observational phenome-wide association study (PheWAS), psoriasis was significantly associated with a higher risk of breast cancer (the tenth version of the International Classification of Diseases [ICD-10] code C50, hazard ratio [HR] 1.23, 95% CI: 1.11–1.38), NMSC (nonmelanoma skin cancer...
patients with diagnosis codes for psoriasis vulgaris, guttate psoriasis, moderate-to-severe psoriasis, or unspecified psoriasis (ICD-10-GM codes L40.0, L40.4, L40.7, and L40.9, respectively) were included in the analyses. Patients with pustular psoriasis (ICD-10-GM codes L40.1, L40.2, and ...
Outcomes The primary outcome was serious infection requiring hospitalization, using previously validated ICD-9-CM codes with an overall positive predictive value of 90.2%.13 Serious infection was defined as a primary inpatient diagnosis code for pneumonia, meningitis/encephalitis, bacteremia/sepsis, cellul...