Psoriasis is a chronic, immune-mediated disorder with cutaneous and systemic manifestations and substantial negative effects on patient quality of life. Psoriasis has a strong, albeit polygenic, genetic basis. Whereas approximately half of the accountable genetic effect of psoriasis maps to the major hi...
The genetics of psoriasis: a complex disorder of the skin and immune system. Hum Mol Genet. 1998; 7 :1537–1545.Balderas J, Bowcock AM. The genetics of psoriasis: a complex disorder of the skin and immune system. Hum Mol Genet. 1998; 7 :1537–1545. doi: 10.1093/hmg/7.10.1537. [...
Psoriasis is an inflammatory immune-mediated disorder which mainly affects the skin but which also has pathogenic effects with systemic impact. It represents a major psychological burden. During the past decade, inflammatory, cardiovascular, metabolic, and neuropsychiatric comorbidities of psoriasis have ...
Genetics and the immune system function play major roles in the appearance of psoriasis. Instead of the immune system protecting the body from viruses, foreign proteins, and bacteria, the immune system in someone with psoriasis “misfires” and attacks healthy cells. This causes inflammation in the...
Psoriasis is an organ-specific autoimmune disorder and is the most prevalent immune-mediated disease in adults. A genetic component increases the susceptibility to psoriasis and the exact etiopathogenesis of psoriasis still needs to be elucidated. Psoriasis is known to be exacerbated by stress and ...
Psoriasis is an immune-mediated (or autoimmune) disorder that occurs when immune cells known as T lymphocytes, or T cells, attack healthy skin cells in both the nonvascular horny outer layer of the skin and its deeper vascular layer. This attack causes the life span of the skin cells to sh...
Stress: Scientists think your immune system may respond to emotional and mental pressures the same way it does to physical problems, such as injuries and infections. Medications: Some treatments can make psoriasis worse. These include: Lithium, which treats bipolar disorder and other mental illnesses...
Dandruff-like scales that flake off and stick to the eyelashes Eye dryness from scales pulling the eyelid outward Pain when moving, opening or closing the eyelids Eyelid psoriasis causes Generally considered a disorder of the immune system, genetics can also play a role in psoriasis (though there...
Stress: Scientists think your immune system may respond to emotional and mental pressures the same way it does to physical problems, such as injuries and infections. Medications: Some treatments can make psoriasis worse. These include: Lithium, which treats bipolar disorder and other mental illnesses...
About 1 in 50 people will develop psoriasis at some point in their life. The disorder is typically chronic and varies in severity from minor localized patches to complete body coverage. It presents with thick, red, scaly patches on the surface of the skin that can get inflamed and start ble...