The PSMA PET scan is an emerging imaging modality with improved sensitivity and specificity over conventional imaging for prostate cancer staging. It uses PET in conjunction with a tracer that is highly effective in detecting prostate cancer throughout the body so the precise location of the...
Aim: The optimal management for early recurrent prostate cancer following radical prostatectomy (RP) in patients with negative prostate-specific membrane antigen positron-emission tomography (PSMA-PET) scan is an ongoing subject of debate. The aim of this study was to evaluate the outcome of salvage...
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Patients’ cancers were understaged by conventional imaging; PSMA-PET results were positive in 84% of patients, PSMA-PET detected M1 disease stage in 46% of patients and found polymetastatic disease (≥5 lesions) in 24% of patients. Meaning Further studies are needed to assess...
than CT and bone scan for staging high-risk disease (evidence level 1b), and that PSMA PET should be offered to men showing a persistent PSA > 0.2 ng/ml, if the result is expected to influence subsequent treatment decisions (weak recommendation) [11,12]. A variety of68Ga- and18F...
As still 44% of the PSMA-11-PET patients had no PSA response, there is still a high need for novel generation imaging further improving SABR outcomes. However, in this regard earlier detection with more sensitive imaging modalities can result in lead time bias, meaning that survival is not ...
PET images were reconstructed using VPFXS (OSEM with time-of-flight and point spread function (PSF) corrections, number of iterations/subsets unknown, pixel spacing: 2.73–3.16 mm, slice thickness: 2.8–3.02 mm). The scan duration was 180 s per bed position. A model-based scatter correction...
The FDA has also approved Locametz®(kit for the preparation of gallium Ga 68 gozetotide injection)2. After radiolabeling, this imaging agent may be used to identify PSMA-positive lesions in adult patients with mCRPC through a positron emission tomography (PET) scan2. Gallium-...
The purpose of this study was to evaluate the effects of decreasing PET scan times on image quality by using three metrics: contrast-to-noise ratio (CNR) in the foci, signal-to-noise ratio (SNR) in the liver, and coefficients of variation (CV) of image noise. Additionally, we evaluated...
The aims of this independent sub-study were to: (i) investigate the inter- and intra-reader agreement of the visual assessment of 68Ga-PSMA-11 PET/CT scans using VISION read criteria for RLT eligibility, and (ii) evaluate the agreement between read results in this study and VISION ...