P. aeruginosa is a ubiquitous microorganism which can survive under a variety of environmental conditions. It causes disease not only in plants and animals, but also in humans, including serious infections in immunocompromised patients and individuals with severe burns and cystic fibrosis .Shouguang ...
Pseudomonas aeruginosa is one of the most important opportunistic bacterial pathogens in humans and animals. This organism is ubiquitous and has high intrinsic resistance to antibiotics due to the low permeability of the outer membrane and the presence of numerous multiple drug efflux pumps. Various ce...
Pseudomonas infection is caused by strains of bacteria found widely in the environment; the most common type causing infections in humans is called Pseudomonas aeruginosa. 假单胞菌感染是由环境中广泛存在的菌株引起的,而感染人类...
Targeting bacterial virulence factors directly provides a new paradigm for the intervention and treatment of bacterial diseases.produces a myriad of virulence factors to cause fatal diseases in humans. In this study, human single-chain antibodies (HuscFvs) that bound toexotoxin A (ETA) were ...
Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes mortality in humans mainly due to respiratory infections caused by Pseudomonas aeruginosa. In a previous work we used phage therapy, which is a treatment with a mix of phages, to actively counteract ...
Pseudomonas aeruginosais an adaptable and resilient Gram-negative bacterium found ubiquitously in the environment [1–3] that is capable of infecting a wide range of organisms, including vertebrates, invertebrate eukaryotes, and plants [4]. In humans, it is responsible for causing keratitis, burn wo...
In humans, P. aeruginosa can infect the urinary tract, respiratory and gastrointestinal system, soft tissues, bones and joints leading to severe systemic infections of immunosuppressed hospitalized patients. 仅用于科研。不用于诊断过程。未经明确授权不得转售。
conditions. Equipped with an equally large repertoire of pathogenic mechanisms,P. aeruginosais capable of infecting eukaryotic organisms ranging from social amoeba to humans. The discussion in this chapter will highlight the metabolic and pathogenic diversity ofP. aeruginosaand the relationship to human ...
Pseudomonas aeruginosa, an opportunistic pathogen, is responsible for various infections in humans, especially among compromised immune systems and people with pre-existing medical ailments [1]. Its ubiquity contributes to substantial illness and mortality within diverse groups, encompassing individuals wit...
aeruginosa in humans. ABSTRACT Pseudomonas aeruginosa is a common Gram-negative opportunistic pathogen that is intrinsically resistant to a wide range of antibiotics. The development of a broadly protective vaccine against P. aeruginosa remains a major challenge. Here, we used an attenuated strain of ...