DHA-PC and PSD-95 decrease after loss of synaptophysin and before neuronal loss in patients with Alzheimer's disease. Sci Rep. 2014;4:7130.Yuki D, Sugiura Y, Zaima N, Akatsu H, Takei S, Yao I, et al. DHA-PC and
[关键词] 突触后致密蛋白 95(PSD95);突触小泡蛋白(synaptophysin);神经元;突触;细胞培养[中图分类号] R392-33,Q343. 6,Q421 [文献标志码] ADistribution of postsynaptic density protein 95 (PSD95)and synaptophysin duringneuronal maturationCHAI Jixia 1 ,WANG Yuanyuan 1 ,LI Huihui 1 ,HE Wenxin 1 ...
[Keywords] Synaptophysin一38(SYN一38);Postsynapticdensity-95(PSD一95); Cerebralischemiainjury; Review 脑缺血一再灌注损伤的病理生理过程是一个多 有大量 的突触囊泡,与神经递质 的释放密切相 环节、多因素、多途径作用的级联反应,神经元的损 关 2【;突触后膜主要为突触后致密物质,突触后致 伤是这一过程的...
Synaptophysin Antibody #4329 100 µl Product Information Product Usage Information ApplicationDilution Western Blotting 1:1000 Immunoprecipitation 1:50 Storage Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the ant...
Staining both PSD95-eGFP and PSD95-mEos2 brain sections for a presynaptic marker (synaptophysin I) revealed presynaptic puncta juxtaposed with PSD95 as expected (Supplementary Fig. 1c). In the PSD95-eGFP mice the expression level of the tagged protein was comparable to that of wild type (...
These clusters likely reflect postsynaptic sites, as they colocalize with synaptophysin (Craven et al. 1999; data not shown). Overexpression of cypin, which shows a diffuse expression pattern in the dendrites of transfected cells, reduces the number of PSD-95 clusters (Figure 7). To quantitate...
Both synapsin and synaptophysin associate with synaptic vesicles and regulate neurotransmitter release [7]. They are concentrated primarily in presynaptic nerve terminals where they appear to mediate interactions of synaptic vesicles with actin filaments and microtubules [6]. Our study showed that the DAB...
方法线栓法建立大鼠的大脑中动脉缺血模型(MCAO),术后第3天起,口服灌注哌醋甲酯,采用免疫组织化学方法观察术后第7、14、28天突触素(Synaptophysin,SYN)及突触后致密物质(Postsynaptic density-95,PSD-95)在大鼠皮层缺血灶的内、外、对侧的表达。 2.
KeyWords:synaptophysin;PSD一95;visualplasticity;synapticplasticity VI 天津医科大学硕士研究生学位论文 英文缩写 BDNF CREB IOD L]DV IJP MD PSD SSV SYN VC VEP 英文缩略语 英文名称 brain-derived neurotrophic factor cAMP responseeleraentbindingprotein ...
3. Chronic antidepressant treatment induces contrasting patterns of synaptophysin and PSA-NCAM expression in different regions of the adult rat telencephalon.[J].Blasco-Ibanez JM;Nacher J;Martinez-Guijarro FJ;Varea E;Castillo-Gomez E;Gomez-Climent MA;Crespo C,European neuropsychopharmacology: the j...