Localization of synapsin-I and PSD-95 in developing postnatal rat cerebellar cortex . Dev Brain Res 151 ( 1–2 ), 25 – 32 .Castejon OJ, Fuller L, Dailey ME. Localization of synapsin-I and PSD-95 in developing postnatal rat cerebellar cortex. Brain Res Dev Brain Res. 2004; 151 :25...
糖尿病胃轻瘫大鼠胃窦PSD95和Synapsin-Ⅰ的表达和意义 田爱霞,钱伟,刘诗 田爱霞,钱伟,刘诗,华中科技大学同济医学院附属协和医院消化内科湖北省武汉市430022 田爱霞,2007年同济医学院附属协和医院硕士生,主要从事胃肠病学方面的研究 国家自然科学基金资助项目,No30670775 ...
synapsin-Ⅰand P-Synapsin- Ⅰin the gastric antrum of rats at weeks 2,4,8 and 12 wk after diabetes induction was detected by real-time PCR and Western blot,respectively.RESULTS:In the diabetic group,the mRNAand protein expression levels of PSD95 and synapsin-Ⅰ at all time points after ...
(Western blot)法检测BDNF,PSD95和synapsin1的蛋白表达水平.结果 麻黄碱呈浓度依赖性降低PC12细胞活力,其引起PC12细胞死亡的IC25和IC50分别为0.536 mmol和2.8 mmol.随着麻黄碱浓度的升高,PC12细胞体积变小,边界模糊,突触数减少,轴突长度减短;BDNF和PSD95的表达水平明显升高;synapsin1的表达水平有所降低.结论 麻黄碱...
Synapsin-1 (D12G5) XP® Rabbit mAb #5297 20 µl PSD95 (D27E11) XP® Rabbit mAb #3450 20 µl SNAP25 (D7B4) Rabbit mAb #5308 100 µl Product InformationProduct Usage Information ApplicationDilution Western Blotting 1:1000 Immunofluorescence (Frozen) 1:100 Immunofluorescence (Imm...
同时降低突触蛋白Synapsin I和PSD95的表达水平,使NMDAR亚基NR2B表达下调,p-ERK的活性降低,提示DEHP长时暴露抑制海马神经元的树突和突触发育;这种抑制效应可能通过雌... 陆阳 - 《浙江师范大学》 被引量: 1发表: 2015年 杜仲叶总黄酮通过RhoA/ROCK信号通路参与脑出血大鼠神经功能修复 杜仲叶总黄酮或RhoA抑制剂干预治...
同时采用免疫组织化学法观察动物的缺血侧脑组织突触素-Ⅰ( synapsin-Ⅰ),突触后致密蛋白95( PSD-95),α-突触核蛋白(α-synuclein)表达情况.结果与假手术组相比,... 刘洋,孙建宁,董世芬,... - 《中国比较医学杂志》 被引量: 24发表: 2012年 山茱萸醇提物调节LSD1/PSD95对Aβ_(25-35)诱导的阿尔茨海默...
Synapsin I (Protein I), a Nerve Terminal-Specific Phosphoprotein. III. Its Association with Synaptic Vesicles Studied in a Highly Purified Synaptic Vesicle Preparation. J Cell Biol. 96, 1374–1388 (1983). 67. Grant, S. G., Marshall, M. C., Page, K. L., Cumiskey, M. A. & ...
We found aberrantly high autophagic activity attributable to a concomitant decrease in mTORC1 signaling, resulting in decreased levels of synaptic proteins, including Synapsin-1 and Shank3. CN2097 increased mTORC1 activity to normalize autophagy and restore hippocampal synaptic protein levels. Importantly,...
Under both paradigms, established cocaine sensitization under non-silenced conditions was associated with enhanced PSD-95 and synapsin I protein expression as well as enhanced Ser845 phosphorylation of the GluR1 subunit on withdrawal day. Silencing ILK expression under both paradigms prevented or reversed...