[29] Börgermann C, Loertzer H, Hammerer P, Fornara P, Graefen M, Rübben H. [Problems, objective, and substance of early detection of prostate cancer]. Urologe A 2010;49(2):181-189. [30] Roobol MJ, Roobol...
这是因为通过PSA检测发现的许多肿瘤生长是这样的缓慢,以至于不太可能危及生命【That is because many tumors found through PSA testing grow so slowly that they are unlikely to be life threatening. 】。检测此类肿瘤被称为“过度诊...
■ The American College of Physicians (ACP) has issued new guidelines for prostate-specific antigen (PSA) testing. In particular, the ACP recommends that men between the ages of 50 and 69 years should only undergo PSA screening after discussing the "limited benefits and substantial harms" of...
Historical prostate-specific antigen (PSA)-based screening studies reduced prostate cancer-related deaths but also led to overdiagnosis/overtreatment. Since then, opportunistic PSA testing has increased, and late-stage diagnoses and prostate-cancer relat
Is additional testing necessary in men with prostate-specific antigen levels of 1.0 ng/mL or less in a population-based screening setting? (ERSPC, section Rotterdam). Urology 2005;65(2):343-346. 摘要 目标:目前,全球不同国家正在使用几种前列腺癌筛 查间隔,从 1 年 ~ 4 年不等.最近,有人提议...
Because of this, the approach to PSA testing has evolved. Today, it is used in a more dynamic way to assess an individual's risk for cancer based on their age, medical history, and other key risk factors. How to Tell Prostate Cancer From an Enlarged Prostate ...
Understand the compliance concerns particular in your industry and area. Ensure that the chosen PSA platform adheres to applicable statistics safety guidelines and industry requirements, minimizing legal and regulatory risks. Trial Period and Testing ...
upgrading and testing - planning, administering, conducting and offering competitions, initiatives, training courses, seminars, meetings, business functions, talks, events and other activities related to PSA's business operation - exercising and performing rights and obligations under or in connection with...
5A). Additional proteolytic activity testing (Fig. 3A) with two peptide substrates, MeO-Suc-RPY-MCA and Mu-HSSKLQ-AMC (Fig. 3B), confirmed that the Thr163 PSA had a lower proteolytic activity towards the fluorescent peptides compared to the Wt PSA protein variant and as expected, the ...
Expert opinions regarding PSA testing are divided; the benefits of early diagnosis must be weighed against the harm caused by overdiagnosis PSA isoforms represent potential biomarkers for monitoring disease Aberrant glycosylation patterns occur when changes to cellular pathways affect glycan processing; thes...