The ProScreen trial is a clinical trial conducted in Helsinki and Tampere, Finland, that randomized 61 193 men aged 50 through 63 years who were free of prostate cancer in a 1:3 ratio to either be invited or not ...
Cluster randomisation makes estimation of the effect of a policy to invite men for screening easier, enhancing the trial's generalisability beyond men consenting to individual randomisation. An 'intention- to-screen' analysis will ensure that individuals will be analysed in the arm their GP practice...
The UK Biobank BPH/LUTS dataset (accessed under Application Number: 24711) consists of 11,178 men with symptomatic BPH/LUTS, according to hospital-based diagnosis (ICD10 code = N40), as well as 176,541 male controls, not known to have been diagnosed with BPH/LUTS. For the UK GWAS ...