PSA testing also plays a crucial role in monitoring patients who have undergone treatment for prostate cancer. In cases where the patient is deemed cancer-free, their PSA levels should decrease to within the normal range. Following radical prostatectomy (removal of the entire prostate), PSA levels...
L. et al. Association of prostate cancer risk variants with gene expression in normal and tumor tissue. Cancer Epidemiol. Biomark. Prev. 24, 255–260 (2015). Article CAS Google Scholar Wu, L. et al. Analysis of Over 140,000 European Descendants Identifies Genetically Predicted Blood Protein...
The average testosterone (13.4 nmol l À 1) was within the normal range as were the other sex hormones: follicle stimulating hormone, 9.2 iu l À 1; luteinizing hormone, 7.4 iu l À 1; sex hormone binding globulin, 41.4 nmol l À 1; and free androgen index, 24.3%. Magnetic ...
Pathology BPH PCa N = 50 Cases Low-risk Intermediate risk High-risk N PCa Recurrence, 1 Year Gleason Score N Age Average Range tPSA ng/mL ±SD Range fPSA ng/mL ±SD Range 29 63.24 44–76 7.59 2.39 3.89–14.47 1.26 0.53 0.30–2.28 7 0% Gleason 5 Gleason 6 1 84 2.45 0.27 6 ...
A range of thresholds of PSA (A) or PSAD (B) were used to predict the presence of clinically significant prostate cancer on biopsy (Negative = no csigPCa, Positive = yes csigPCa). Each bar represents how accurate each threshold would be if used as a clinical test to predict for csig...
Cells membrane-engineered with 0.25 µg/mL anti-PSA antibody demonstrated a statistically lower response against the upper (≥4 ng/mL) PSA concentration range. In addition, the cell-based biosensor performed better than the immunosensor in terms of sensitivity and resolution against positive samples...