On the other hand, for patients undergoing hormone therapy or active surveillance, the target PSA level may be set at a level that indicates stable disease or slow progression. It is important to note that PSA levels alone cannot definitively diagnose or monitor prostate cancer. Other factors, ...
IQR indicates interquartile range; PSA, prostate-specific antigen. aIndicates that the practice could not provide a list of men aged 50 to 69 years registered at the practice usually because it treated a subset of the UK population (eg, homeless, elderly care home). bThese practices took ...
The expected normal level of total PSA in male serum is lower than 4 ng/mL. A rise in the concentration of PSA indicates prostate pathology, including benign prostatic hyperplasia and prostate cancer. 注:本产品仅用于科研用途,不能直接用于人体或临床诊断使用。 公司简介 深圳市豪地华拓生物科技...
As seen in the table a small number of men with a low PSA level may still have prostate cancer although this is usually likely to be at a very early stage. A normal result for a man over 55 can be reassuring as it indicates you are unlikely to have an aggressive cancer at the time...
Traditionally, clinicians have used prognostic factors such as disease stage, tumour grade, nodal status and pre-treatment prostate-specific antigen (PSA) level to stratify patients for risk of disease recurrence after primary therapy. More recently, evidence from a number of studies indicates that ...
to its usual carrier molecules, the protease inhibitors; free PSA is used to distinguish prostate CA from BPH, etc; free PSA levels are measured in Pts with a total PSA level between 4 and 10 ng/mL and nonsuspicious digital rectal examinations; ↑ free PSA indicates a ↓ risk of CA....
At the cellular level, PCa contains differentiated cancer cells expressing high levels of PSA (i.e., PSA+), as well as PCa cells that express little or no PSA (i.e., PSA−/lo). The PSA−/lo cells appear to be rare in early-stage tumors but become more abundant in high-grade ...
The study was aimed at assessing the diagnostic performance of 68Ga-PSMA-617 PET/CT in the detection of prostate cancer (PCa) in patients with a prostate-specific antigen (PSA) level of 4–20 ng/ml and to compare its efficacy with that of multiparam
In addition, expression of HDAC1 (P=0.032), HDAC2 (P=0.002) and HDAC3 (P<0.001) correlated significantly with the Ki-67-positive proliferative fraction of prostate cancer cells (Table 1). This indicates that the interlink between HDAC activity and cell differentiation, as well as cell ...
- 《Prostate》 被引量: 114发表: 1998年 Detection of residual prostate cancer after radical prostatectomy with the Abbott IMx PSA assay Objectives. This analysis was performed to define the level of serum prostate-specific antigen (PSA) measured with the Abbott IMx assay that indicates resi... ...