Discordant prostate specific antigen test results despite WHO assay standardization. Int J Biol Markers. 2018 Aug;33(3):275-282. 摘要 介绍:总 PSA(t PSA)和游离 PSA(f PSA)是早期检 测前列腺癌最常用的生物标志物.尽管进行了标准化 工作,但目前使用的许多 PSA 检测方法可能产生不一 致的结果.在本...
Our results demonstrate a multivariate model of the Prostate Screening Test (PSE) consisting of the standard continuous PSA test readout with specific set of blood-based, established PCa EpiSwitch biomarkers from the regulatory genome architecture of chromosome conformations (Episwitch). When tested in...
Results 2.1. Clinical and Pathological Characteristics of the Patients A cohort of 79 serum samples containing 29 BPH and 50 PCa samples was used for the study of the two blood-based biomarkers, PHI and the percentage of α2,3-sialic of PSA. PCa staging was determined according to the ...
While digital rectal examination of the prostate gland may fail to detect cancer at an early stage, routine screening in blood for the prostate-specific antigen (PSA), a 28.4 kD serine protease secreted by the epithelial lining of the periurethral glands and the prostatic epithelium, has ...