A detailed summary on the genotype, age at diagnosis, family history, Gleason Grades, Gleason Score and PSA levels at diagnosis were obtained. Immunohistochemical (IHC) staining was performed using FFPE sections (4 µm) incubated with anti-PSA antibody (1:5000) (Dako; Catalogue number #A...
We estimated the genetic correlation between pairs of traits using the cross-trait LD score regression method26and the summary statistics from the Icelandic and UK datasets. In this analysis we used results for about 1.2 million variants, well imputed in both datasets, and for LD information we ...
Summary and concluding remarks Taken together, our data demonstrate altered emotional responses in adulthood following exposure to stressors during juvenility which were coupled with altered development-related changes in the expression of totalNCAM and its posttranslationally modified form totalPSA-NCAM. Th...
(SF-36) Physical Component Summary (PCS) score19; at week 16, proportion of patients achieving a Static Investigator Global Assessment (sIGA) of Psoriasis of 0 or 1 and at least a 2 point improvement from baseline (sIGA 0/1) for patients with baseline sIGA ≥220; Psoriasis Area Severity ...
Summary Introduction European Randomized Study of Screening for Prostate Cancer (ERSPC) mortality results were reported for 7 European countries (excluding France) and showed a significant reduction in Prostate cancer (PCa) mortality. As those results have not been part of the global ERSPC results, ...
Key outcomes were improvements in Health Assessment Questionnaire Disability Index and Short Form-36 Physical Component Summary Score, proportion of non-radiographic progressors and predictors of sustained LDA response. Results Patients were randomised (N=996) into the following treatment groups: ...
Simple Summary: The widespread use of PSA for prostate cancer diagnosis significantly contributed to the high rate of overdiagnosis and overtreatment. For several years, the Prostate Health Index (PHI) has been proposed as a tool able to improve PSA specificity. More recently, the Proclarix test ...
After the Ad step, the oxygen purity can reach up to 76.5%, In summary, for current radial-flow PSA oxygen generation, CP-π flow is shown to be the optimal type based on the above flow characteristics, and is therefore selected to be further explored for its advantageous oxygen generation...