Beyond the intended superdisintegrant use (facilitation of dosage form disintegration), the biopharmaceutical implications of superdisintegrants on drug solubility, drug permeability or drug–excipient interactions are not fully understood. The pH of the medium affects the performance of SSG and CCS due...
The longer form mAKAPα is preferentially expressed in the brain. However, mAKAPβ, which is the shorter form of the scaffolding protein that lacks the first 244 amino acids, was found to be preferentially expressed in the heart at the nuclear envelope of cardiomyocytes [40]. It was first ...