The pruritus associated with these conditions greatly impacts patients' quality of life and lacks uniformly effective treatment. A 57-year-old patient presented with severe atopic dermatitis and subsequent prurigo nodularis refractory to numerous standard therapies. The supplement isoquercetin was initiated ...
Figure 2. Clinical Improvement in Patients With Prurigo Nodularis (PN) and Chronic Pruritus of Unknown Origin (CPUO) With Abrocitinib Treatment View LargeDownload Panels A and B show the percent change from baseline in weekly Peak Pruritus Numeric Rating Scale (PP-NRS) scores in the intention-...
DEG, differentially expressed gene; Fc, fold change; FDR, false discovery rate; H, matched healthy control sample; L, lesional; NL, nonlesional; PN, prurigo nodularis; RNA seq, RNA sequencing. Lesional PN skin shows Th17/Th22 skewing mRNA sequencing revealed that lesional PN samples expressed...
Treatment-resistant prurigo nodularis: challenges and solutions. Clin Cosmet Investig Dermatol. 2019 Feb;12:163–72.10.2147/CCID.S188070Search in Google Scholar PubMed PubMed Central [40] Zhang J, Fang H, Wang R, Dang E, Jiang M, Wang G. Effect of calcipotriol on IFN-gamma-induced ...