在ClinicalTrials.gov进行一个完整方案注册,需要填写的内容几乎涵盖了临床试验的方方面面,大致可以分为研究方案名称和背景 资料、FDA相关信息、受试者评审信息等12部分内容。 有的需要在有限的选项中选择一项或多项,如研究类型;有的需要注册者自行填写,如研究方案说明。 在临床试验实施过程中,随着试验的进展以及研究方...
A systematic review was performed of randomised controlled trials on smoking cessation interventions in patients with COPD reporting 12-month biochemical validated abstinence rates. The different interventions were grouped...doi:10.1016/S1098-3015(11)72262-8M Hoogendoorn...
which are not a concern for the active clinical studies but do not support long-term use and progression to later-stage development. AstraZeneca’s decision was made independent of any data from t...
This systematic review aims to evaluate the effectiveness of early mobilization compared to delayed mobilization of the elbow after ulnar nerve decompression. Methods: Randomized controlled trials (RCTs) and observational studies comparing adults who received early mobilization or late mobilization were ...
This review has been registered with PROSPERO (CRD42018077115). The literature search generated 13 unique articles. Seven articles were included for full text screening and 3 articles met our inclusion criteria, all of which were level II evidence with low risk of bias (165 patients). Pooled ...