Interleukin-1α is a suggested dual-function cytokine that diverged from interleukin-1β in mammals potentially by acquiring additional biological roles that relate to highly conserved regions in the pro-domain of interleukin-1α, including a nuclear localisation sequence and histone acetyltransferase-bind...
Proximity labeling is widely used to identify the spatial context of the proteome via genetically encoded enzymes using small molecules as tags to label the surrounding environment1,2,3,4. This technique is a promising alternative for spatial biologists to systematically map localized proteins in situ...
Note: this unit label is translatable/customizable with the facetwp_i18n hook. The default text is also translatable with a translation plugin or a WordPress gettext filter (see this example). Radius UI The UI element to use for the radius selector (“Dropdown”, “Slider”, or “None”)...
Creates a new proximity placement gruup witht he specified name and then adds it to the availability set. Parameters: proximityPlacementGroupName - The name of the group to be created. type - the type of the group Returns: the next stage of...
displayStatus string The short localizable label for the status. level StatusLevelTypes The level code. message string The detailed status message, including for alerts and error messages. time string The time of the status. Intent Specifies the user intent of the proximity placement g...
α-Synuclein proximity ligation assay (PLA) has proved a sensitive technique for detection of non-Lewy body α-synuclein aggregate pathology. Here, we describe the MJF-14 PLA, a new PLA towards aggregated α-synuclein with unprecedented specificity, using the aggregate-selective α-synuclein antibody...
(2012). From learning region to learning in a socio-spatial context. Regional Studies, 46(8), 981–992. https://doi.org/10.1080/00343404.2012.712679 (Open in a new window)Web of Science ®(Open in a new window)Google Scholar Short, J. R., Kim, Y., Kuus, M., & Wells, H. ...
To investigate the molecular basis of binding of these compounds in comparison to known sites of action of GBR 12909, cocaine, and benztropine analogs, we developed a piperidine-based photoaffinity label [(125)I]4-[2-(diphenylmethoxy)ethyl]-1-[(4-azido- 3-iodophenyl)methyl]-piperidine [(125...
A function to be called each time a response is received from the server while performing the requested operation. May be called multiple times. TypeScript Copy onResponse?: RawResponseCallback Property Value RawResponseCallback Inherited From coreClient.OperationOptions.onResponse...
Proximity labeling can label the targeting molecules directly in the region of interests which overcomes the shortcomings of fractionation-based methods. APEX220,21,22 and BioID23 have been used in investigating the SG proteome24. However, BioID is incapable of labeling RNA, while APEX221,25 req...