Gene ID: 5629 种属 Homo sapiens DNA序列编号: NM_001270616.2 DNA描述 Homo sapiens prospero homeobox 1 (PROX1), transcript variant 1, mRNA DNA大小: 8468 bp DNA编码区: atgcctgaccatgacagcacagccctcttaagccggcaaaccaagaggagaagagttgac attggagtgaaaaggacggtagggacagcatctgcattttttgctaaggcaagagcaacg ttt...
PROX1 geneAtherosclerosisBMICardiometabolic indexCarotid femoral pulse wave velocityBackground Atherosclerosis is a primary risk factor for cardiovascular disease, but its pathogenesis is unclear. Previous studies reported that the prospero homeobox 1 (PROX1) gene is associated with lipid disorders and ...
The dentate gyrus has an important role in learning and memory, and adult neurogenesis in the subgranular zone of the dentate gyrus may play a role in the acquisition of new memories. The homeobox gene Prox1 is expressed in the dentate gyrus during embryonic development and adult neurogenesis. ...
Dr Guillermo Oliver, senior author of the study, explained that the findings raise the possibility that mutations in the Prox1 gene may be related to learning and memory problems. 'The more we understand about how signalling pathways work in the brain, the more we will eventually be able to...
Gene Typeprotein_coding Uniprot IDQ92786.2 Pathway/Libraryothers Gene SummaryThe protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA...
Prospero homeobox 1 (PROX1) has been shown to function as a tumor suppressor gene or oncogene in various types of cancer, including oral squamous cell carcinoma (OSCC). We have previously identified PROX1 as a downregulated gene in OSCC. The aim of this study is to clarify the underlying ...
Gene Type protein_coding Uniprot ID Q92786.2 Pathway/Library others Gene Summary The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA ...
提供的PRRG1单克隆抗体(M05), 克隆号1C7产品为小鼠源单克隆抗体,对应的抗体亚型为IgG2a Kappa。该基因又称PRGP1,全名为proline rich Gla (G-carboxyglutamic acid) 1。对应Gene号为NM_000950,其蛋白编号为NP_000941.1。 应用类型 IHC-P,IF,ELISA,WB-Re ...
Prox1 (Prospero-related homeobox 1) is a divergent homeogene that regulates cell proliferation, fate determination and differentiation during vertebrate embryonic development. The protein is expressed in the developing lens and is also detected in embryo
We suggest that dysregulation of PROX1 gene expression due to separation from its conserved upstream elements is likely to have caused the heart defects observed in this patient, and that PROX1 should be considered as a potential candidate gene for other cases of HLH. The relevance of another ...