ProTx-II (ProTx-2, Protoxin II)is a toxin that was originally isolated from Thrixopelma pruriens (Peruvian green velvet tarantula).ProTx-IIinhibits bothtetrodotoxin-sensitiveandtetrodotoxin-resistantvoltage-gated sodium channels.ProTx-IIinhibits activation by shifting the voltage-dependence of channel...
Biotinyl-ProTx-II(生物素-原毒素 II) ProTx-II (Protoxin-II) is a toxin that was originally isolated from Thrixopelma pruriens (Peruvian green velvet tarantula).ProTx-II inhibits both tetrodotoxin-sensitive and tetrodotoxin-resistant channels. ProTx-II inhibits activation by shifting the voltage-...
ProTx-II inhibits both tetrodotoxin-sensitive and tetrodotoxin-resistant voltage-gated sodium channels. ProTx-II inhibits activation by shifting the voltage-dependence of channel activation to more positive potentials. ProTx-II blocks Nav1.7 with an IC50 value of around 300 pM, Nav1.2, Nav1.5 and...
(Peruvian green velvet tarantula). ProTx-II inhibits both tetrodotoxin-sensitive and tetrodotoxin-resistant voltage-gated sodium channels. ProTx-II inhibits activation by shifting the voltage-dependence of channel activation to more positive potentials. ProTx-II blocks Nav1.7 with an IC50 value of ...