如上图所示,与两个最先进的方法ProteinDT和ProtST相比较,ProTrek在大多数功能类别上展现出卓越的性能,无论使用氨基酸序列编码器还是3Di结构编码器。在全局检索任务中,ProTrek的性能比ProteinDT和ProtST提高了30倍以上和60倍以上。 02 蛋白功能相似性搜索 实验综合评估ProTrek在搜索功能相似蛋白质方面的能力,与多个已...
Input (We recommend describing the protein's properties rather than using a simple numerical value like an EC number) Retrieve top k results Input examples Proteins with zinc bindings. Proteins locating at cell membrane. Catalyzes the hydrolysis of cutin, a polyester that forms the structure of...
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Furthermore, TREK–1 knockdown and fluoxetine administration directly reduced the differentiation of fibroblasts to myofibroblasts by inhibiting the focal adhesion kinase (FAK)/p38 mitogen-activated protein kinases (p38)/Yes-associated protein (YAP) signaling pathway. In conclusion, TREK–1 plays a ...
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