Radiation therapy (RT) plays a fundamental role in the treatment of malignant and benign brain tumors. Current state-of-the-art photon- and proton-based RT combines more conformal dose distribution of target volumes and accurate dose delivery while limiting the adverse radiation effects. PubMed ...
摘要: Compared with photon radiation (XRT), proton beam radiation therapy (PBRT) reduces dose to normal tissues, which may lead to better neurocognitive outcomes. We compared change in intelligence quotient (IQ) over time in pediatric patients with brain tumors treated with PBRT versus XRT....
Lymphatic vessels were detected in the tumor-skin border of the control and P groups; however, they were also present in the core of the X tumors (Figure 4c), finding consistent with the over-expression of Oncogenesis (2017), 1 – 13 Proton versus photon radiation impact in squamous cell...
Poster ‐ 31: Predicting IQ and hearing loss following radiotherapy in pediatric brain tumors: proton vs photonProtonsBrainCancerDeafnessDosimetryIntensity modulated radiation therapyPhotonsAuditory system modelsTissuesPurpose:The increased sparing of normal tissues in intensity modulated proton therapy (IMPT) ...
Effect of photon vs. proton radiation on tumor cell viability In the UPS cell culture group, no significant differences in cell viability were visible between photon and proton irradiation after four days (supplementary Fig. 5A). Eight days after irradiation, there was a slightly higher cell-killi...
The second toxicity level should estimate whether the probability of radiation induced normal tissue toxicity for the patient is different between different treatment plans. The third cost-effectiveness level should evaluate if the extra costs for a certain increase in effectiveness does not exceed a ...
1 Proton therapy, after its introduction, has also been utilized for the treatment of prostate with mainly conventional fractionation, demonstrating a similar clinical outcome to that of photon therapy.2, 3 Over the past ten years, hypofractionation was introduced to proton therapy and has been ...
Radiation Oncology volume 18, Article number: 189 (2023) Cite this article 1846 Accesses Metrics details Abstract Purpose To discuss the optimal treatment modality for inoperable locally advanced Non-Small Cell Lung Cancer patients with poor physical status, impaired cardio-pulmonary function, and ...
Radiobiological risk estimates of adverse events and secondary cancer for proton and photon radiation therapy of pediatric medulloblastoma. Introduction. The aim of this model study was to estimate and compare the risk of radiation-induced adverse late effects in pediatric patients with medullo... Bro...
The use of proton beams for radiation treatment in cancer therapy has become more prevalent during the past decade, with technology evolutions such as pencil beam scanning and single vault solutions helping to drive the increased utilization and access. While much work has been done to increase the...