LIQUID DOSAGE FORM OF PROTON PUMP INHIBITORPROBLEM TO BE SOLVED: To provide a liquid suspension vehicle comprising micro-granules comprising a proton pump inhibitor.TANEJA RAJNEESHラジネーシユタネジヤ
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Vonoprazan Fumarate (TAK-438F) is a new and effective drug approved in Japan in 2014 for treatment and prevention of acid-related diseases (ARDs), which exhibits many advantages compared with traditional proton-pump inhibitors (PPIs). However, the clinical applications of TAK0-438F suffers limita...
Racemic proton pump inhibitors (PPIs) have been developed into pure enantiomers given superior pharmacokinetic profiles. However, after doses of single enantiomer PPIs, different degrees of chiral inversion were observed. We investigated the relationship between chiral inversion and reductive metabolism of ...
1.an apparatus for drawing or forcing liquid or gas. 2.to draw or force liquids or gases. blood pumpa machine used to propel blood through the tubing of extracorporeal circulation devices. breast pumpa pump for taking milk from the breast. ...
Three new compounds were designed on the basis of the structure of the proton-pump inhibitors omeprazole and lansoprazole, maintaining the 2-(2-pyridylmethylsulfinyl)-1H-benzimidazole core. A methyl group at position 5 of benzimidazole ring replaced the methoxy group, the rest of substitutions were...
the simultaneous enantioselective determination of proton-pump inhibitors (PPIs-omeprazole, lansoprazole, pantoprazole, and rabeprazole) in environmental water matrices based on solid-phase extraction combined with dispersive liquid-liquid microextraction (SPE-DLLME) and chiral liquid chromatography-tandem mass ...
IN Papadoyannis,KI Nikolaidou,VF Samanidou - 《Journal of Liquid Chromatography & Related Technologies》 被引量: 188发表: 2008年 Analytical errors in the determination of high field strength elements and their implications in tectonic interpretation studies The quality of analytical data obtained from...
(freezable, liquid-like).69,172The three states of water arise from very different interactions of water with its immediate surroundings, making the quantity of each, and therefore the overall water diffusion behavior, directly dependent upon morphology within the membrane. The general procedure to ...
Examples of proton pump inhibitors according to formula I are The acid susceptible proton pump inhibitors used in the dosage forms of the invention may be used in their neutral form or in the form of an alkaline salt, such as for instance the Mg2+, Ca2+, Na+, K+or Li+salts, preferably...