Purpose Patients with node-positive (LN+) uterine or cervical cancer often require postoperative radiation therapy (RT) to the pelvis and para-aortic nodes. A prospective phase 2 study was conducted to evaluate
November 10, 2009 (Chicago, Illinois) — Proton-beam therapy will replace conventional radiation in the curative treatment of cancer in the next 10 to 15 years, said one enthusiastic proponent of the technology during a press conference here at the American Society for Radiation Oncology (ASTRO) ...
A comparative effectiveness review of proton beam therapy by the Veteran's Health Administration (2015) reached the following conclusions: "For the cancer sites and types reviewed by the ESP report, there are no reliable data from long-term randomized trials on survival, quality of life, or func...
Reduction in quality of life due to retardation of growth and development and secondary cancer are also significant problems in pediatric patients.2, 3 Particle therapy, including proton beam therapy (PBT), has unique physical properties that allow for the reduction or elimination of unnecessary ...
Proton therapy is an advanced cancer treatment technique that delivers highly targeted dose to the tumour while sparing surrounding normal tissue, enabled by the finite range of the proton beam. This precision targeting, however, is compromised by tumour motion or anatomical changes throughout a cours...
The treatment effectiveness of cancer is closely related to advances in radiation therapy technology [18]. Protons, as particles, are different from photons such as X-rays and gamma rays; they continuously slow down as they change in depth. This process of dose deposition creates the characteristi...
Biodistribution studies using an MDA-MB-231 breast cancer xenograft mouse model revealed significant potential for enhancing radiation therapy, because the boron uptake in the tumor was notably high, with a very slow rate of decrease, which is an important result for therapeutic effectiveness. With ...
Ions provide a more advantageous dose distribution than photons for external beam radiotherapy, due to their so-called inverse depth dose deposition and, in particular a characteristic dose maximum at their end-of-range (Bragg peak). The favorable physical interaction properties enable selective treatme...
Proton therapy allows for more conformal delivery of RT. A prospective phase II study was conducted to evaluate the safety and efficacy of proton beam RT for patients with LN+ uterine or cervical cancer, including dosimetric comparison and quality of life. Materials/Methods Patients with IIIC ...
Proton therapyLiverSpread-out Bragg peakSecondary particlesNoninvolved organsRadiation for targeting liver tumors can be challenging because of the damage that it can cause to sensitive organs such as heart and kidney. To calculate the dose received by noninvolved organs, a modeling of the patient'...