Purpose Patients with node-positive (LN+) uterine or cervical cancer often require postoperative radiation therapy (RT) to the pelvis and para-aortic nodes. A prospective phase 2 study was conducted to evaluate the efficacy of proton beam RT for LN+ uterine or cervical cancer. Methods and Mater...
Proton therapy allows for more conformal delivery of RT. A prospective phase II study was conducted to evaluate the safety and efficacy of proton beam RT for patients with LN+ uterine or cervical cancer, including dosimetric comparison and quality of life. Materials/Methods Patients with IIIC ...
A comparative effectiveness review of proton beam therapy by the Veteran's Health Administration (2015) reached the following conclusions: "For the cancer sites and types reviewed by the ESP report, there are no reliable data from long-term randomized trials on survival, quality of life, or func...
Reduction in quality of life due to retardation of growth and development and secondary cancer are also significant problems in pediatric patients.2, 3 Particle therapy, including proton beam therapy (PBT), has unique physical properties that allow for the reduction or elimination of unnecessary ...
Proton therapy is an advanced cancer treatment technique that delivers highly targeted dose to the tumour while sparing surrounding normal tissue, enabled by the finite range of the proton beam. This precision targeting, however, is compromised by tumour motion or anatomical changes throughout a cours...
The treatment effectiveness of cancer is closely related to advances in radiation therapy technology [18]. Protons, as particles, are different from photons such as X-rays and gamma rays; they continuously slow down as they change in depth. This process of dose deposition creates the characteristi...
Ions provide a more advantageous dose distribution than photons for external beam radiotherapy, due to their so-called inverse depth dose deposition and, in particular a characteristic dose maximum at their end-of-range (Bragg peak). The favorable physical interaction properties enable selective treatme...
Radiation Dose phantom was used for liver proton therapy simulation.The results show that the optimum proton energy interval covering the whole tumor was in the range of 90-120 MeV.A spread-out Bragg peak was built by adding Bragg peaks to cover the liver tumor volume,and beam parameters ...
Randomized phase IIB trial of proton beam therapy versus intensity-modulated radiation therapy for locally advanced esophageal cancer J Clin Oncol, 38 (2020), pp. 1569-1579 CrossrefGoogle Scholar [11] S.H. Lin, K.W. Merrell, J. Shen, V. Verma, A.M. Correa, L. Wang, et al. Multi-...
Conclusions Proton beam radiotherapy affords excellent dosimetric parameters and low toxicity in patients with esophageal cancer treated with curative intent. Prospective trials are underway investigating the comparative benefit of proton-based therapy.