This has resulted in a steady increase in the Impact Factor of PPL to it's current level of 1.849. We anticipate that this will continue to climb, especially with the large number of special Hot Topics issues we have published in 2011 and the ones planned for 2012. Of equal importance ...
This thesis presents several models and algorithms that address three main areas of open research problems in bioinformatics: (1) mass-spectrometry based proteomics, (2) biclustering in systems biology motivated by DNA microarray data, and (3) the clustering of molecular compound libraries in drug ...
Proteomics is an emerging field that aims to comprehensively analyse the complete set of proteins expressed by an organelle, cell, tissue, organism, or population (McArdle and Menikou2021). Proteomics approaches have been applied to various areas of biology, including human health, plant, and anim...
Over the past decade, systems biology and plant-omics have increasingly become the main stream in plant biology research. New developments in mass spectrometry and bioinformatics tools, and methodological schema to integrate multi-omics data have leveraged recent advances in proteomics and metabolomics. ...
Over the past decade, systems biology and plant-omics have increasingly become the main stream in plant biology research. New developments in mass spectrometry and bioinformatics tools, and methodological schema to integrate multi-omics data have leverag
Proteomicsis an intermediate bridge technology for systems biology in the postgenetic era. As the executor of life activities and functions,proteomicsstudies the composition, activity rule and protein–protein interaction in cells from the overall level (Aslam et al., 2016). In the field of oilomi...
Calmodulin Kinase and Contraction, Cancer - General, Cardiac muscle regeneration, Cardiovascular Pharmacogenomics, Cell Biology, Signaling & Cell Circuits, Cell death pathways, Cell Processing System in Cell Therapy Process Development, Cerebrovascular and Neurodegenerative Diseases, Chemical Biology and its re...
With the advancement in the technology, it is possible now to obtain comprehensive views of the biological systems and to study large patient cohorts in a streamlined manner. In this review we discuss the technological advancements in mass spectrometry–based proteomics, which allow analysis of ...
Hepatocellular carcinoma (HCC) is a malignant tumor associated with high global incidence and mortality rates. Proteomics, as a platform technology of cellular protein expression, modification, and interaction, has provided innovative perspectives on early diagnosis, treatment, and targeted drug development...
This chapter introduces Systems Biology, its context, aims, concepts and strategies, then describes approaches used in genomics, epigenomics, transcriptomics, proteomics, metabolomics and lipidomics, and how recent technological advances in these fields have moved the bottleneck from data production to dat...