In this issue of Proteomics – Clinical Applications you will find the following highlighted articles: TODO: clickthrough URL Hi ho SELDI, away! That closing cry of the Lone Ranger meant that everything was under control. The bad guy was either dead or in jail, the good guy had his job ...
Technologies to shape the future: proteomics applications in anesthesiology and critical care medicine. Anesth Analg. 2006;102(4):1207–16. Article PubMed CAS Google Scholar Attal N. Neuropathic pain: mechanisms, therapeutic approach, and interpretation of clinical trials. Continuum (Minneap Minn)....
Krone N, Hughes BA, Lavery GG, Stewart PM, Arlt W, Shackleton CH. Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS). J Steroid Biochem Mol Biol...
MongoDB DashboardThe continuous integration pipeline has the action “Performance test pyinstaller”. This action freezes the current Python environment into an executable and runs the test files. The results of these tests are uploaded to a noSQL database (MongoDB) for the tested version number....
1D, the gel areas encased by the dash-lined rectangles were excised from the gel for trypsin digestion followed by LC-MS/MS analysis. Of note, a flow chart provided in Fig. 2 summarizes each step in the experimental design during the affinity purification of Agno-associated proteins followed...
PROTEOMICS
[120,121]. Several pathogenic viruses including HIV, influenza virus, SARS, and Zika virus, are known to use host-derived glycosylation events to build their glycoproteins on the virion surface, both N-linked and O-linked, to infect their target host cells [119]. Similar to other coronavirus...
Recent advances in stem cell and proteomic technology carry tremendous potential to impact our understanding of mechanistic underpinnings and fundamental pathophysiology of cardiovascular disease. In this chapter, we introduce investigators new to these disciplines to the various types of stem cells relevant...
When BRCA1 breaks The most frequent cancer among women, breast cancer arises principally due to mutations in the tumor suppressor genes, BRCA1 and BRCA2/FANCD1 . Carriers of BRCA1 mutations have a 50–80% chance of breast cancer by age 70. BRCA1 is highly multi-functional, its most ...