Log In Sign Up Subjects Tech and Engineering How are proteins made and what do they do?Question:How are proteins made and what do they do?The Proteome:The proteome is the full complement of proteins in a given type of cell or tissue under specific conditions. The proteome, unlike the...
The first is to determine what changes (if any) the proposed alterations are likely to have on the characteristics of the protein. The second is to determine whether the alterations in the protein characteristics have clinical consequences. The risk due to the proposed change is then a product ...
What makes intranasal administration of insulin very attractive are not only the unique features of nasal mucosa already mentioned throughout this review (high vascularization, lower enzyme concentrations in comparison with gastrointestinal tract, avoidance of first-pass metabolism) but also the pharmacok...
What 2 organelles produce proteins? What does the nucleus do in protein synthesis? What molecule holds instructions for the synthesis of proteins? Proteins are made during the process of What are the monomer "building blocks" that make up proteins?
The manganese/iron-carboxylate proteins: what is what, where are they, and what can the sequences tell us?doi:10.1007/s00775-009-0606-5Heterodinuclear - Metal specificity - Redox tuning - Oxygenase - ReductaseThe manganese/iron-carboxylate proteins make up a recently ...
Proteins Proteins can have up to four different levels of organization, and assume a 3-dimensional shape Function of Proteins… Proteins serve many different functions: 1. Muscles provide structural support and motion (actin and myosin) 2. Help fight disease (antibodies) 3. Regulate cell processes...
In the process, they made an unexpected discovery:myosin, one of the three main proteins that make up striated muscle fibers, appears to enter the Z-disc. Models of how myosin, actin and the elastic scaffold protein titin work together have largely ignored the possibility that myosin filaments...
What is a meaningful representation of protein sequences?. Nicki Skafte Detlefsen, Søren Hauberg, Wouter Boomsma. Preprint, November 2020. [arxiv] Profile Prediction: An Alignment-Based Pre-Training Task for Protein Sequence Models. Pascal Sturmfels, Jesse Vig, Ali Madani, Nazneen Fatema Raja...
An important consequence of the concept of holoimmunity is that the same immunological mechanisms that determine "self"-"nonself" also operate to regulate what microbes can participate as non-pathogenic components of the host microbiome. Microbiome microbes mimic host antigens. Thus, HIV mimicry of...
Current research in molecular biology is highly engaged in compiling a “horizontal”, rather descriptive, catalog of protein sequences with their biological roles, but the “vertical” investigation of the physicochemical mechanisms of how proteins perform their functions (i.e., what eventually would...