We hope that this will be a useful resource for people interested in the field. To the best of our knowledge, this is the first public, collaborative list of machine learning papers on protein applications. We try to classify papers based on a combination of their applications and model type...
aHowever,in the body,oxidation is not a onestep,semiexplosive reaction but acomplex,slow stepwise process called catabolism,which liberates energy in small,usable amounts.Energy can be stored in the body in the form of special energy-rich phosphate compounds and in the form of proteins ,fats,...
Inhibition of SCD1 impairs palmitate-derived autophagy at the step of autophagosome-lysosome fusion in pancreatic β-cells Autophagy is indispensable for the proper architecture and flawless functioning of pancreatic β-cells. A growing body of evidence indicates reciprocal com... J Janikiewicz,K Hanz...
Researchers have identified 13 proteins in the blood that predict how quickly or slowly a person’s brain ages compared with the rest of their body. Their study1, published inNature Agingon 9 December, used a machine-learning model to estimate ‘brain ages’ from scans of more than 10,000...
Andrews explains, "Shrimp and other seafood are good for your heart because they contain selenium—an antioxidant that protects the cells in your body from free radical damage." Additionally, seafood is a source of omega-3 fatty acids, which support heart health by reducing inflammation and ...
Integrating both types of data can reveal exciting biology and is an essential step in refining our understanding of the principles of gene expression control. This is a preview of subscription content, access via your institution Access options Access Nature and 54 other Nature Portfolio journals ...
The protocol is optimized to avoid undesired reduction in binder diversity and enrichment of non-specific binders to ensure the best possible selection outcome. Using the efficient fragment exchange (FX) cloning method, the sybody sequences are transferred from the phagemid to different expression ...
mediator. However, other genes including MmedOBP11-13, 15-17, 19-20 appeared to be expressed at higher levels in body parts than in antennae. Focusing on the functional characterization of MmedCSP3, immunocytochemistry and fluorescent competitive binding assays were conducted indoors. It was found...
Here, we find that most APRs are unique within a proteome, but that a small minority of APRs occur in many proteins. When aggregation is nucleated in bacteria by such frequently occurring APRs, it leads to massive and lethal inclusion body formation containing a large number of proteins. ...
(Fig.1iand Supplementary Fig.1c). Because the antibodies against the endogenous TCTN1 showed signals in cell bodies of thetctn1cells, which lost TCTN1 protein, it was very possible that the staining of the cell body was nonspecific. Consistent with previous studies for other TZ protein, TCT...