Exocytosis is catalyzed by the engagement of SNARE proteins embedded in the plasma membrane with complementary SNAREs in the membrane of trafficking vesicles undergoing exocytosis. In most cells studied so far, SNAREs are not randomly distributed across the plasma membrane but are clustered and ...
GMP-140 is an integral membrane glycoprotein found in secretory granules of platelets and endothelial cells. After cellular activation, it is rapidly redis... GI Johnston,RG Cook,McEver, Rodger P. - 《Cell》 被引量: 1690发表: 1989年 Requirement of CD9 on the Egg Plasma Membrane for Fertili...
This chapter discusses the importance of plasma membrane proteins in carrying out numerous cellular functions at the interface between the internal and external environments. The plasma membrane is actively involved in the uptake by endocytosis of a variety of materials from the surrounding medium. The...
Plasma membrane-associated proteins with the ability to partially inhibit perforin-mediated lysi Muller, S, Hasselkus-Light, CS, Young, JD, Jiang, S.Plasma membrane-associated proteins with the ability to partially inhibit perforin-mediated lysis. ... DM Ojeius,S Muller,CS Hasselkus-Light,......
Molecules intimately associated with thecell membranelink cells to the extracellular matrix. These molecules, called matrixreceptors, bind selectively to specific matrix components and interact, directly or indirectly, withactinprotein fibres that form thecytoskeletoninside the cell. This association of actin...
Starvation, cyclic nucleotide levels and cell contact have been implicated in the control of plasma membrane protein synthesis. Developmentally regulated changes in the plasma membrane proteins of another species, Polysphondylium pallidum , are described since they provide interesting comparisons with ...
They are released with their contents (proteins, lipids, sugars and nucleic acids) into the extracellular space upon fusion with the plasma membrane. Exosomes contribute to the spread of neurotoxic proteins. Exosomes in cerebrospinal fluid, blood and urine are stable and useful as biomarkers. ...
We recently demonstrated that in the absence of TatB, TatC is sufficient to insert RR-precursor proteins into the plasma membrane of E. coli even to a point where they become prematurely processed by signal peptidase18. We now sought to follow the track of such an inserted RR-precursor on ...
The functional coupling between TRH receptor and Gq/11α was assessed by agonist-stimulated [35S]GTPS binding, and results of these measurements pointed out to significantly lower potency of TRH to mediate G protein activation in the plasma membrane fraction isolated from cholesterol-depleted cells;...
First, almost all α-helical MPs require the membrane-embedded translocon for insertion14. While some outer membrane β-barrels are able to insert spontaneously into lipid vesicles15, the majority of them require the β-barrel assembly machinery (BAM) for insertion in vivo16,17. The exact ...