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Proteins are remarkable molecular machines: they digest your food, fire your neurons, power your immune system and so much more. What if we could design new ones, with functions never before seen in nature? In this remarkable glimpse of the future, David Baker shares how his team at the In...
What are monomers of the organic compounds below? 1. carbohydrates 2. lipids 3. nucleic acids 4. proteins What is the name of the monomer that makes up proteins? A molecule of DNA contains two polymer strands, in which bonding of the building blocks of what, are put t...
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Made of amino acid chains with specific sequences, proteins are biological workhorses. As natural protein sequences are encoded in cellular DNA, these chains fold into three-dimensional conformations. The sequence of the amino acids in the chain guides where it will bend and twist, and how part...
But only some 170,000 of them have had their structures determined. Dr Moult thinks that boosting this number could help screen drug candidates to see which are likely to bind well to a particular protein. It could be used to reanalyse existing drugs to see what else they might do. And ...
protein folding is often primarily determined by protein topology. Moreover, folding studies on small globular proteins showed that rate constants are inversely correlated with total contact order, which reflects the average distance between native contacts in the amino acid sequence31. What all of ...
Analysis of the correspodence between theoretical results and the results for certain fibrous proteins and polymers has been made. This analysis shows that in some parts of these substances there are regions where the parallel chains are arranged without any correlation to the packing of the units ...
2.3.1Role of blood cells and proteins on biomaterial surfaces Blood is a complex biological fluid made up of plasma, cells and proteins. There are thousands of uniqueblood proteinsand some are present at high concentrations, for instance, albumin (35–50mg/mL) andfibrinogen(2–4mg/mL), respe...
Cilia are microtubule-based hair-like organelles propelling locomotion and extracellular liquid flow or sensing environmental stimuli. As cilia are diffusion barrier-gated subcellular compartments, their protein components are thought to come from the ce