Metalloenzymes are 40% of all enzymes and can perform all seven classes of enzyme reactions. Because of the physicochemical similarities between the active sites of metalloenzymes and inactive metal binding sites, it is challenging to differentiate between them. Yet distinguishing these two classes i...
The main function of proteins is to act as enzymes. Almost all chemical reactions in living systems are catalysed by enzymes, and all known enzymes are proteins. It is at first sight paradoxical that it is probably easier for an organism to produce a new protein than to produce a new ...
functions carried out by G protein-coupled receptors (GPCRs), which are transmembrane proteins; the nuclear factors of activated T cells (NFATs), which are transcription factors; and the Src family kinases (SFKs), which are signaling enzymes, are all modulated by the collaboration of PTMs and...
Enzymes that digest proteins into smaller fragments. In shotgun proteomics, proteins are digested into peptides by sequence-specific proteases (such as trypsin, which cleaves proteins at the carboxy-terminal side of lysine and arginine residues). Lipopolysaccharide (LPS). A structural component of the...
. Adjacent in the Halobacteria genomes are two families found in the core module 1 (fam00008 and fam00115) and annotated as digeranylgeranylglycerophospholipid reductase and UbiA prenyltransferases respectively (Additional file1: Table S7). Closer inspection of these three co-encoded enzymes inHalo...
Thus even a decade later plant enzymes have still been barely studied because the conservative nature of many of the biochemical pathways means that similar enzymes are more readily available elsewhere. Even when there are enzymes unique to plants, such as photosynthetic enzymes, these have not ...
Nearly half of the proteins that associate with the OMV fraction are involved in virulence either being part of the TTSS, putative virulence factors or cellulytic enzymes. From the results presented in this study we conclude that plant pathogenic bacteria like Xcc can liberate membrane- and ...
Dendrites have a unique microtubule organization. In vertebrates, dendritic microtubules are organized in antiparallel bundles, oriented with their plus ends either pointing away or toward the soma. The mixed microtubule arrays control intracellular traf
Membrane proteins carry out many essential functions in biology and are therefore major drug targets1,2. Recent progress has been made in understanding how membrane proteins fold3, but while lipid–protein interactions are known to be important, their precise roles remain unclear, with most informati...
Pathogenesis-related 10 (PR-10) is a group of small intracellular proteins that is one of 17 subclasses of pathogenesis-related proteins in plants. The PR-10 proteins have been studied extensively and are well-recognized for their contribution to host de