The types of amino acids that significantly contribute to evolutionary rates can be grouped into GC-rich and AT-rich amino acids. Besides, the amino acid with high composition also contributes more to evolutionary rates than amino acid with low composition in proteome. In summary, amino acid ...
the GRA16-fused nuclear proteins SMN1, TFEB and MeCP2 successfully localized to both the PV and host cell nucleus. This indicates that these proteins were successfully targeted to the dense granules, secreted to the PV, exported to the host cell cytosol and accumulated...
This paper presents a novel approach, in which a discrete feature extraction method is fused with physicochemical properties of amino acids by using Chou's general form of Pseudo Amino Acid Composition. The technique is tested on two benchmark datasets namely: Gpos-mploc and Virus-mPLoc. The ...
amino acid variables,the best fit was provided by a regression including the Fischer ratio and cystathionine,which explained 55% of the variability of cholesterol (multiple r~2 = 0.55 p< 0.0001),and this result was not improved by the inclusion of other amino acids.These data show that ...
It was demonstrated that formaldehyde reacts first with the amino and thiol groups of amino acids and forms methylol derivatives. In the case of primary amino groups, the methylol groups partially undergo condensation to an imine, also called a Schiff-base (Scheme 1). Subsequently, the imine ...
2a, b. Most dietary proteins or peptides are absorbed actively by ECs in non-sensitised persons by endocytosis at the apical membrane and undergo transcytosis toward the lamina propria (LP). An estimate of 70–90% of the transported protein is degraded by intracellular enzymes into amino acids...
PROGRESS OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids Veit Hornung, Rune Hartmann, Andrea Ablasser and Karl-Peter Hopfner Abstract | Recent discoveries in the field of innate immunity have highlighted the existence of a family of nucleic acid-sensing...
Signal peptides of wall anchored proteins encompass the canonical tripartite structure where a short, basic n-region precedes a longer hydrophobic stretch of amino acids (h-region), followed by the c-region with the recognition sequence for the enzyme signal peptidase (see Chapter 9) [40], [...
Electrostatic forces between basic amino-acids and phosphate groups contribute to the stability of the complexes, but selective recognition requires more specific interactions which are not yet understood. The recognition of a specific region of a nucleic acid could be explained if this region has ...
22. The nucleic acid of claim 21, wherein said CCR-protein encoded by said nucleotide sequence has an amino acid sequence at least 60% homologous to an amino acid sequence represented in SEQ ID No. 2. 23. The nucleic acid of claim 21, wherein said CCR-protein encoded by said nucleoti...