Here we show that mammalian VCP is trimethylated on Lys315 in a variety of cell lines and tissues, and that the previously uncharacterized protein METTL21D (denoted here as VCP lysine methyltransferase, VCP-KMT) is the responsible enzyme. VCP methylation was abolished in three human VCP- KMT ...
The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates Magnus E. Jakobsson Jędrzej M. Małecki Pål Ø. Falnes Nature Communications (2018) Association between SNPs and haplotypes in the METTL21C gene and peak bone mineral...